Leucemia Linfocitic Cronica Flashcards

1
Q

qué es

A

Acumulación de LB monoclonales en la médula ósea glanglios linfáticos hígado y bazo

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2
Q

Edad mas frecuente

A

65 años en el 90%

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3
Q

Etiología

A

Desconocida VHC?

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4
Q

Anormalidades citogenicas

A

Delecion del cromosoma 13q

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5
Q

Síntomas en fases avanzadas

A

Síntomas B

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6
Q

Síndrome de Richter

A

Transformación de Linfoma de células grandes

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7
Q

Causa de afección a SNC

A

Infecciones oportunistas: criptococosis y losteriosis

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8
Q

Laboratorio 🧪

A

Linfos 5000-600000
Anemia
Trombocitopenia

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9
Q

Tipo de anemia

A

Normocitica normocromica y retis normales

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10
Q

Supervivencia desde el dx

A

2-20 años

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11
Q

Sistemas de valor pronostico

A

Sistema Rai y Binet

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12
Q

Estadios pronósticos precarios

A

Estadios III Y IV

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13
Q

Tratamiento de estadios tempranos

A

Diferido

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14
Q

Tratamiento de estadios avanzados

A

Al momento del dx

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15
Q

Agente terapéutico de elección

A

Fludarabina

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16
Q

Aplicación paliativa en al cito reducción ganglionar y esplenica

A

RT

17
Q

Supervivencia prolinfocitica y Richter

A

6 meses

18
Q

Aumento de cancer

A

Cutáneo
Color rectal
Pulmonar