LECTURE exam 4- Ch. 23 Flashcards
- interstitial fluid (fluid in between cells)
- lymphocytes (primary for immune response; circulate in lymphatic fluid)
- macrophages (engulf unknown things)
lymph
- pass through lymphatic tissue & organs
- deliver lymph to venous circulation
lymphatic vessels
- thymus
- red bone marrow
primary lymphatic structures
- tonsils
- lymph nodes (axillary, lumbar, pelvic, inguinal)
- spleen
- mucosa (associated lymphoid tissue)
secondary lymphatic structures
- produce, maintain & distribute lymphocytes
- provide alternative transport route
- maintain normal blood volume & composition of interstitial fluid
functions of lymphatic system
- cause differentiation of lymphocytes resulting in: T cells, B cells & NK cells
primary lymphatic structures
“front line” defense
- consist of lymphocytes & B cells
secondary lymphatic structures
- hormones
- nutrients: lipids transferred by lacteal system are carried to the bloodstream via lymphatic vessels
- waste products
functions of lymphatic system: provide alternative transport route
relatively high capillary pressure forces ___ & ___ out of plasma into interstitial fluid area
solutes & water
- small
- only found in places with vasculature
- lacteals are specialized capillaries in SI
lymphatic capillaries
larger-diameter lymphatic vessels
lymphatic ducts
whats A
incomplete basal lamina
whats B
lymphatic valve
- larger in diameter
- thinner walls
- irregular outline
- anchoring filaments that connect to surrounding connective tissue keep capillaries open
- greater permeability
lymphatic capillaries
- thinner walls & larger lumens
- do not have easily identifiable tunics
- have valves just like most veins
- pressure is lower than veins
- skeletal muscle contraction helps propel lymph
- inhalation decreases thoracic pressure, which helps to move lymph toward venous system
lymphatic vessels
- subcutaneous layer
- mucous lining of digestive, respiratory, urinary & reproductive tracts
- serous lining of pleural, pericardial, & peritoneal cavities
superficial lymphatics
skeletal muscle, neck, limbs, trunk & visceral organs
deep lymphatics
convergence of deep & superficial
lymphatic trunks
- thoracic duct drain
- right lymphatic drain
all trunks drain into one of two ducts
right side of body superior to diaphragm: arm/ torso /neck & head
right lymphatic drains
- labeled A
- lymph inferior to the diaphragm: abdomen / both legs
- left side of body superior to diaphragm: arm / torso / neck & head
thoracic duct drains
- labeled B
primary cells of lymphatic system
lymphocytes
- invading bacteria & viruses
- abnormal body cells such as cancer cells
- foreign proteins such as toxins released by some bacteria
lymphocytes respond to –
- exit bloodstream to enter interstitial spaces
- re enter bloodstream via lymphatic vessels
lymphocytes travel throughout the body
- originate in bone marrow but travel to the thymus gland & become immunocompetent (activated) by thymosin
- mature cells leave thymus & migrate to red bone marrow & spleen
T cells
attack foreign cells & viruses
cytotoxic T cells
stimulate T & B cells; enhance antibody production
Helper T cells
moderate immune response
regulatory T cells
activated upon subsequent antigen exposure
memory T cells
- originate & become immunocompetent in bone marrow
- mature cells enter bloodstream & migrate to peripheral tissues
B cells
Can differentiate to form:
- plasma cells (produce antibodies that react with antigens)
- memory B cells (become activated if same antigen reappears)
B cells
- attack foreign cells
- attack normal cells that are infected with viruses
- attack cancer cells
NK cells
both lymphatic tissue & lymphatic nodules are lymphatic tissues without a ___
capsule
- mucosa-associated lymphoid tissue (MALT)
- tonsils (5 sets)
- aggregated lymphoid nodules (Peyer’s patches & appendix)
types of nodules