Lecture 7 Flashcards
Increase in cell size =
Increase in metabolic demands
Which increases at a faster rate: volume or surface area
Volume
Metabolic demands is determined by
Volume of cell
Transport of materials is determined by
Surface area
The smaller an object is,
The more surface area/ the less volume
The smaller an object is, the smaller the volume and larger the surface are which is why
Cells are small
To maintain homeostasis cell must have
Enough surface area
(Can’t work if metabolic demand > exchange of materials)
All cells :
-surrounded by membrane
-cytosol inside cytoplasm
-dna
-ribosomes
Prokaryotic cells have
Dna not in nucleus, lack most organelles
Eukaryotic cells have
Dna in nucleus, organnelles
Cell membrane role
Boundary between outside and inside
Cell membrane functions
-membrane transport (selectively permeable)
-cell signalling (sense changes and react)
-cell adhesion
Components of cell membrane
- Protein molecules
- Lipid molecules
Substance inside cytoplasm
Cytosol
Nucleus stores what
Dna
What is the nuclear envelope
Two membranes (outer and inner), boundary if nucleus
Nuclear pores
Gateways allowing molecules to enter/leave nucleus (ex mRNA to transcript genetic code)
Nucleolus
Mass of densily stained granules/fibers
Site of ribosome synthesis (rRNA)
Ribosomes are formed with
rRNA and a little protein
Ribosomes synthesize proteins in
Cytosol (free ribosomes)
Outside of RER (bound ribosomes)
Proteins synthesized outside of RER for
Outside of cell, functions inside specific organelles, integration into membranes
Proteins synthesized in cytosol are
Intracellular (not secretory)
Endoplasmic reticulum (ER) structure
Same as plasma membrane (phospholipid bilayer continuous with nuclear envelope with proteins)
Two types of ER
Smooth ER (lack ribosomes)
rough ER (surface studded with bound ribosomes)
Smooth ER functions
- Synthesis of lipids
- Break down stored glycogen
- Detoxification of drugs and poisons
Rough ER functions
- Protein synthesis (specifically secretory)
- Membrane sythesis
Golgi apparatus functions
-modifies lipids and proteins produced by ER
-sorting station
-packaging/export of molecules
Golgi apparatus looks like
Flattened sacs called cisternae, surrounded by vesicles
Vacuoles are
Large vesicles
Functions of vesicles
Store/transport chemicals throughout the cell
What produces vesicles
ER and golgi
Lysosomes are
Specialized vesicles
Lysosomes do what
Intracellular digestion (degrade damaged or unneeded macromolecules, bacteria)
Lysosomes can digest all biological molecules but
Enzymes optimal at pH 5
Peroxisomes contain enzymes that
-Detoxify harmful substances
-Produce hydrogen peroxide (can be toxic to cell, so
-Convert hydrogen peroxide to water and O2
Peroxisomes
Found mainly in liver and kidney
Plays role in breaking down/synthesizing FA
Endomembrane system defines
Physical relationship between many organelles within eukaryotic cell
Organelles in endomembrane syst have an interrelated membrane through
Direct contact of transfer if membrane (vesicles)
They are related by form
Overall role of endomembrane system :
Regulate prot traffic in cell and perform various metabolic functions
Components of endomembrane system
- Plasma membrane
- Nuclear envelope of nucleus
- ER
- Golgi apparatus
- Lysosomes
- Vesicles and vacuoles