Lecture 21 - Urinary Flashcards

1
Q

components of the kidney

A

cortex (renal corpuscles) and medulla (tubules only) which contain the calyces. Covered by a fibrous capsule

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2
Q

Renal corpuscle

A

golmerulus and capsule filters blood

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3
Q

Proximal tubule

A

convoluted tubule (65% of reabsorption) and a straight short duct. Enters the outer medulla from the cortex

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4
Q

Loop of Henle

A

thick descending (15% of reabsorption), thin descending, thin ascending, and thick ascending duct. Occurs in the medulla

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5
Q

Distal tubule

A

thick ascending duct and thick convoluted tubule. reenters the cortex and has the macula densa.

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6
Q

glomerulus

A

large bed of capillaries in the corpuscle.

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7
Q

Cell type in the corpuscle and their function

A

podocytes that aid in the filtration of the blood.

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8
Q

Macula densa

A

highly compacted cells of the distal convoluted tubule adjacent to the arteriole. can control the flow of blood into the renal corpuscle. by secreting renin to the juxtaglomerular cells.

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9
Q

Parietal layer of the corpuscle

A

capsule

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10
Q

Visceral component

A

highly branched arterioles and capillaries that are surrounded by podocytes that aid in the filtration into the urinary space outside the blood vessels and then connected by the proximal convoluted tubule.

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11
Q

Pedicles

A

branches from podocytes that cover the capillaries. will form the filtration slits

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12
Q

What are cell sin the macula densa sensitive to?

A

sodium chloride concentration in the distal convoluted tubule. a decrease will cause an increase in blood flow in the afferent arteriole

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13
Q

Mesangial cells

A

help clean the basement membrane surrounding the capillaries.

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14
Q

Which tubule will have a prominent microvilli brush border?

A

proximal convoluted tubule and thick descending tubule

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15
Q

Filtration membrane

A

fluid passes from the capillary lumen through fenestrations across a thick basement membrane and through thin slit diaphragms between pedicles of podocytes and into Bowman’s space

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16
Q

Thin ascending absorption

A

NaCl but not water

17
Q

Aldosterone’s role in kidneys

A

promotes sodium and water reabsorption in the distal convoluted tubule and collecting ducts.

18
Q

Vasopressin’s role in kidneys

A

increases permeability of collecting ducts to water which is osmotically pulled from the filtrate.

19
Q

Vasa recta

A

bed of capillaries surrounding the loop of Henle.

20
Q

Peritbular capillaries

A

capillaries associated with convoluted tubules.

21
Q

Outer stripe of medulla

A

Thick and thick

22
Q

Inner strip of medulla

A

Thick (ascending) and thin (descending)

23
Q

Inner zone of medulla

A

Thin and thin

24
Q

Collecting duct appearance

A

intercellular borders. Minimal mitochondria

25
Q

Ureters epithelium

A

transitional epithelium or urothelium and surrounded by smooth muscle

26
Q

Whats a histologically distinct feature of transitional epithelium

A

binucleated cells