Lecture 21 - Urinary Flashcards
components of the kidney
cortex (renal corpuscles) and medulla (tubules only) which contain the calyces. Covered by a fibrous capsule
Renal corpuscle
golmerulus and capsule filters blood
Proximal tubule
convoluted tubule (65% of reabsorption) and a straight short duct. Enters the outer medulla from the cortex
Loop of Henle
thick descending (15% of reabsorption), thin descending, thin ascending, and thick ascending duct. Occurs in the medulla
Distal tubule
thick ascending duct and thick convoluted tubule. reenters the cortex and has the macula densa.
glomerulus
large bed of capillaries in the corpuscle.
Cell type in the corpuscle and their function
podocytes that aid in the filtration of the blood.
Macula densa
highly compacted cells of the distal convoluted tubule adjacent to the arteriole. can control the flow of blood into the renal corpuscle. by secreting renin to the juxtaglomerular cells.
Parietal layer of the corpuscle
capsule
Visceral component
highly branched arterioles and capillaries that are surrounded by podocytes that aid in the filtration into the urinary space outside the blood vessels and then connected by the proximal convoluted tubule.
Pedicles
branches from podocytes that cover the capillaries. will form the filtration slits
What are cell sin the macula densa sensitive to?
sodium chloride concentration in the distal convoluted tubule. a decrease will cause an increase in blood flow in the afferent arteriole
Mesangial cells
help clean the basement membrane surrounding the capillaries.
Which tubule will have a prominent microvilli brush border?
proximal convoluted tubule and thick descending tubule
Filtration membrane
fluid passes from the capillary lumen through fenestrations across a thick basement membrane and through thin slit diaphragms between pedicles of podocytes and into Bowman’s space