Lecture 19: Cerebellum - A Flashcards

1
Q

Functions of the cerebellum?

A
  1. Equilibrium and coordination of eye movements
  2. Maintain muscle tone and posture
  3. Coordinate and adjust (mid-course corrections) motor movements
  4. Planning and programming voluntary movements
  5. Motor learning
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

True or False: The cerebellum is considered to be a component of the motor system and has connections with the motor cortex, as well as receives inputs from regions of cerebral cortex/SC associated w/sensory information

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

True or False: The cerebellum functions as the conscious level, with all of the information the the cerebellum processes reaching level of consciousness

A

False - it functions at unconscious level

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Each cerebellar hemisphere assists in movement of the ____ 1/2 of the body
A. bilateral
B. contralateral
C. ipsilateral

A

C. ipsilateral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

___: The obvious, transversely oriented folds of the cerebellar cortex that greatly increases the SA of the cerebellum

A

Folia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which two deep fissures run transversely, dividing cerebellum into the three major lobes?

A

Primary Fissure
Posterolateral Fissure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

True or False: Lobes are further divide into lobules by other deep, transverse fissures

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which lobe is located anterior to the primary fissure?

Which lobe is posterior to both the primary and posterolateral fissures?

Which lobe is anterior posterolateral fissure?

A. Anterior Lobe
B. Posterior Lobe
C. Flocculonodular Lobe

A

A. Anterior Lobe

B. Posterior Lobe

C. Flocculonodular Lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

____: The midline region of the cerebellum

A. Peduncles
B. Vermis
C. Nodulus

A

Vermis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

____: Commonly used name to describe well-defined vermis lobule of the flocculonodular lobe

A. Peduncles
B. Vermis
C. Nodulus

A

C. Nodulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which cerebellar peduncle contains mostly afferents from the spinal cord and the inferior olive?
A. Inferior Cerebellar Peduncle
B. Middle Cerebellar Peduncle
C. Superior Cerebellar Peduncle

A

A. Inferior Cerebellar Peduncle (Restiform Body)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

True or False: The Inferior Cerebellar Peduncle (Restiform Body) contains does efferents - mainly to vesibular nuclei and brainstem reticular formation

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which cerebellar peduncle contains afferents ONLY from pontocerebellar projections of the contralateral basilar pontine nuclei?
A. Superior Cerebellar Peduncle
B. Inferior Cerebellar Peduncle
C. Middle Cerebellar Peduncle

A

C. Middle Cerebellar Peduncle (Brachium pontis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which cerebellar peduncle contains mostly EFFERENTS from the deep cerebellar nuclei to the thalamus (VL) and red nucleus?
A. Superior Cerebellar Peduncle
B. Inferior Cerebellar Peduncle
C. Middle Cerebellar Peduncle

A

A. Superior Cerebellar Peduncle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The Superior Cerebellar Peduncle contains some afferents, mostly those from the ____ _____ tract
A. ventral spinocerebellar tract
B. dorsal spinocerebellar tract
C. lateral spinocerebellar tract

A

A. ventral spinocerebellar tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the three layers of the Cerebellar Cortex of the Cerebellum?

A
  1. Molecular Layer
  2. Purkinje Cell Layer
  3. Granular Cell Layer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which layer of the cerebellar cortex is relatively cell-free, primarily containing 1) Purkinje dendrites, 2) Granule cells axons, and 3) small interneurons?

A. Molecular Layer
B. Purkinje Cell Layer
C. Granular Cell Layer

A

A. Molecular Layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which layer of the cerebellar cortex contains ~15 mil Purkinje cell bodies that project to the deep cerebellar nuclei?

A. Molecular Layer
B. Purkinje Cell Layer
C. Granular Cell Layer

A

B. Purkinje Cell Layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Which cell is the only neuron of the cerebellar cortex to project OUT of the cerebellar cortex?

A. Glial Cell
B. Astrocyte
C. Purkinje Cell

A

C. Purkinje Cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

The granular cells of the Granular Cell Layer of the Cerebellar Cortex function as ____, which excite Purkinje neurons

A

interneurons

21
Q

The granular fibers of the Granular Cell Layer of the Cerebellar Cortex give rise to parallel fibers which synapse on ___ cell dendrites in the molecular layer of the cortex
A. Purkinje cell
B. Granule cell
C. Astrocyte

A

A. Purkinje cell

22
Q

True or False: Each Purkinje cell gets synaptic input from many granule cells

A

True

23
Q

True or False: The cerebellar cortex receives some cerebellar afferents and regulates neurons in the superficial cerebellar nuclei

A

False - the cerebellar cortex receives ALL cerebellar afferents and regulates neurons in the DEEP cerebellar nuclei

24
Q

Which w major layer of the cerebellum?

A

1) Cerebral Cortex
2) Medullary Layer

25
Q

The medullary layer of the cerebellum (white matter) contains both cerebellar cortex ___ and ___ fibers, and comprise central core of each folium

A

efferent; afferent

26
Q

What are the two types of cerebellar cortex afferents found in the medullary layer of the cerebellum?

A
  1. Climbing Fibers
  2. Mossy Fibers
27
Q

Climbing Fibers (afferents in the medullary layer) project to and terminate on dendrites of ___ cells

A. Granule
B. Purkinje

A

B. Purkinje

28
Q

Mossy Fibers (afferents of the medullary layer) project to and terminate on ___ cells

A. Granule
B. Purkinje

A

A. Granule

29
Q

True or False: Climbing Fibers carry “training” information related to movements whereas Mossy Fibers carry “state” information about muscles, internal, and external environment

A

True

30
Q

True or False: Mossy Fibers have numerous sites of origin, can enter cerebellum through inferior, middle, and superior cerebellar peduncles

A

True

31
Q

Where do Climbing Fibers enter the cerebellum?

A

Through the ICP

32
Q

Which two cell types are Cerebellar Cortex Efferents and found in the Medullary Layer?

A
  1. Purkinje neurons
  2. Deep cerebellar nuclei
33
Q

Where do Purkinje neurons (cerebellar cortex efferents - medullary layer) project and terminate on?
A. Neurons in deep cerebellar nuclei
B. Neurons in superficial cerebellar nuclei

A

A. Neurons in deep cerebellar nuclei

34
Q

The Deep Cerebellar Nuclei (cerebellar cortex efferents–medullary layer) exit the cerebellum via which two locations?

A
  1. Superior cerebellar peduncle
    Terminate: red nucleus/VL nucleus of thalamus
  2. Juxtarestriform body
    Terminate: Vestibular nuclei + brainstem reticular formation
35
Q

What are the four deep cerebellar nuclei of the Medullary Layer (Cerebellum) that are embedded in the white matter?

A
  1. Fastigial nucleus
  2. Globose nucleus
  3. Emboliform nucleus
  4. Dentate nucleus
36
Q

Which functional division of the Cerebellum is the oldest part and consists primarily of the (1) Flocculonodular Lobe and the (2) Fastigial Nucleus?
A. Spinocerebellum
B. Vestibulocerebellum
C. Pontocerebellum

A

A. Spinocerebellum

37
Q

What are the two separate subdivisions of the spinocerebellum?

A

Vermal and Paravermal

38
Q

Which three structures does the spino-cerebellum receive input from?

A
  1. Ipsilateral SC
  2. Ipsilateral Trigeminal System
  3. Contralateral Primary Motor Cortex
39
Q

True or False: The overall circuitry of the spinocerebellum allows for coordination of motor movements based on current proprioception information

A

True

  • Allows for midcourse corrections
40
Q

Spinocerebellar tracts (unconscious proprioception) are associated with _____

Mesencephalic nucleus of trigeminal (unconscious proprioception) are associated with _____

A

Ipsilateral Spinal Cord

Ipsilateral Trigeminal System

41
Q

The primary motor cortex projects to the ipsilateral pontine nuclei in the basilar pons via the ____ projections

A

corticopontine projections

42
Q

Pontine nuclei project to the contralateral cerebellar cortex via pontocerebellar projections in the ____ cerebellar penducle
A. dorsal
B. ventral
C. lateral
D. middle
E. inferior

A

D. middle

43
Q

True or False: The vermal portion of the spinocerebellum consists of the cortex of the vermis + fastigial nucleus

A

True

44
Q

The vermis gets proprioceptive info concerned with axial musculature via which tract?

A

Spinocerebellar tract (DSCT, VSCT)

45
Q

Describe this:

A
46
Q

Which of the following system regulates accuracy of leg, head, trunk, and eye movements?
A. Spinocerebellar
B. Cerebrocerebellar
C. Pontocerebellar

A

A. Spinocerebellar - vermal portion

47
Q

Explain this figure:

A
48
Q

Explain this figure:

A