Lecture 14 9/19/24 Flashcards
What are the types of descriptive studies?
-case report
-case series
-survey
What are the types of observational analytical studies?
-cross-sectional
-case-control
-cohort
What are the types of experimental analytical studies?
-controlled trials
-laboratory
What are the most important values of studies?
quality: critical proof/evidence and internal validity
relevance: practical reality and external validity
What is internal validity?
having no major methodological problems or biases
What is external validity?
ability to generalize the results to the target population
What are the basic components of a study?
-study pop.
-determining “treatment” or “risk factor” groups
-assessment of outcomes
-analysis of differences in outcomes between groups
-interpretation of analysis
-extrapolation of results from study pop. to target pop.
What are the basic steps of a study?
-hypothesis
-reference pop.
-study pop.
-selection of individuals/groups
-follow-up or trace-back
-statistical analysis
-interpretation
Which steps of a study contribute to external validity?
-hypothesis
-reference population
-study population
-selection of individuals/groups
Which steps of a study contribute to internal validity?
-selection of individuals/groups
-follow-up or trace-back
-statistical analysis
-interpretation
How do experimental studies differ from observational studies?
experimental: researcher manipulates some factor to see the impact on the outcome
observational: no manipulation by researcher; researcher simply observes what is occurring in “real world”
How do experimental studies compare to observational studies in terms of validity?
-experimental studies often have high internal validity but lower external validity
-observational studies are more prone to bias but have higher external validity
What is confounding bias?
when the researcher fails to consider all possible causes of an outcome and falsely assumes that one cause is the result of the outcome when it could be another
What is the purpose of the control group?
to compare the treatment/risk factor group to something in order to determine if there is an effect