Lecture 1 8/22/24 Flashcards
What is epidemiology?
study of disease in its natural habitat
What is descriptive epidemiology?
description of population characteristics, such as occurrence of disease by individual, time, and place
What is analytical epidemiology?
examination of etiology and associations by comparing two or more groups
How does descriptive epidemiology differ from analytical epidemiology?
descriptive:
-describes patterns and formulates hypotheses
-answers the questions what, who, where, and when?
analytical:
-involves analysis of data to test hypotheses
-answers the questions why and how?
What is clinical epidemiology?
application of epidemiological principles to clinical care in terms of diagnosis, prognosis, treatment, and prevention
What are the three components of the epidemiologic triad?
-agent
-host
-environment
What is a direct disease causation pathway?
a known factor is able to directly cause the disease
What is an indirect disease causation pathway?
a known factor leads to other steps that eventually cause the disease
What are the four types of causal relationships?
-necessary and sufficient
-necessary, but not sufficient
-sufficient, but not necessary
-neither sufficient nor necessary
What are the characteristics of a necessary and sufficient causal relationship?
-the identified factor is both necessary for disease to develop and sufficient to cause disease on its own
-without the factor, the disease never develops
-in the presence of the factor, the disease always develops
-rare pattern; rabies is closest example
What are the characteristics of a necessary, but not sufficient causal relationship?
-each factor is necessary, but none of the factors alone are sufficient to cause disease
-multiple factors are required, often in a specific sequence
What are the characteristics of a sufficient, but not necessary causal relationship?
-the identified factor alone can produce the disease, but so can other factors that are acting alone
-criteria of being sufficient is rarely met by a single factor
What are the characteristics of a neither sufficient nor necessary causal relationship?
-each factor by itself is neither sufficient nor necessary to cause the disease
-combinations of different factors cause the disease
-most accurate representation of most chronic diseases