Lecture 10 9/12/24

Question 1

What does SnNout mean?

Answer 1

with a highly sensitive test, a negative result helps rule a disease out

Question 2

When is a sensitive test best?

Answer 2

-early in the work-up when narrowing a differential list
-when penalty to miss the disease is high

Question 3

Which type of error is reduced with a highly sensitive test?

Answer 3

type 2 error/false negative

Question 4

What does SpPin mean?

Answer 4

with a high specific test, a positive test result helps rule a disease in

Question 5

When is a specific test best?

Answer 5

-later in the work-up once other data suggests a target disease
-useful for when a false positive would result in physical, emotional, or financial loss

Question 6

Which type of error is reduced with a highly specific test?

Answer 6

type 1 error/false positive

Question 7

What is the strategy behind serial testing?

Answer 7

-any negative test makes individual negative
-maximizes specificity and PPV
-lowers sensitivity and NPV

Question 8

What is the strategy behind parallel testing?

Answer 8

-any positive test makes the individual positive
-maximizes sensitivity and NPV
-lowers specificity and PPV