Lecture 12 Part II - Protozoans & Parasites Flashcards
Example of Fungus-Like Protists
slime molds
Three Types of Protists
- Fungus-Like Protists
- Algae
- Protozoans
Three Types of Protozoa
- Amoeba
- Ciliates/Paramecium
- Flagellates
Entamoeba histolytica causes
amoebic dysentery (severe case of amebiasis)
pseudopods
false feet
How do amoebas move?
pseudopods
cilia
short, hair-like projections that allow the cell to move as well as movement of surroundings
How do Trichomonas vaginalis move?
flagella
What is the only type of cell in the human body to have a flagella?
sperm
Trichomonas vaginalis is what type of disease?
STD
STD
sexually transmitted disease
cyst AKA
oocyst
oocyst
is a dormant cyst
algal blooms
excessive growths of algae
What can cause algal blooms?
eutrophication from excessive N & P from fertilizers
Giant Kelp is ______.
Brown Algae
Agar is _______.
Red Algae
Plankton AKA
dinoflagellates
(unicellular, free-swimming algae)
Some plankton (dinoflagellates) produce _________.
neurotoxins
Why are Red Tides dangerous?
Red Tides are excessive growth of dinoflagellates (plankton) which produce neurotoxins and can poison fish, shellfish, and humans.
Diatoms are a type of _______.
Algae
What are protozoan phyla based on?
rRNA sequences
4 Major Protozoan Phyla
- Archaezoa
- Amoebozoa
- Apicomplexa
- Euglenoza
2 Major Species in the Archaezoa Phylum
- Trichomonas vaginalis
- Giardia lamblia
Major Species in the Amoebozoa Phylum
- Entamoeba histolytica
3 Major Species in the Apicomplexa Phylum
- Toxoplasma gondii
- Plasmodium spp.
- Cryptosporidium spp.
2 Major Species in the Euglenozoa Phylum
- Trypanosoma brucei gambiens
- Trypanosoma cruzi
Trichomonas vaginalis belongs to which Protozoan Phylum?
Archaezoa
Giardia lamblia belongs to which Protozoan phylum?
Archaezoa
Entamoeba histolytic belongs to which Protozoan phylum?
Amoebozoa
Toxoplama gondii belong to which Protozoan phylum?
Apicomplexa
Plasmodium spp. belongs to which Protozoa phylum?
Apicomplexa
Cryptosporidium spp. belong to which Protozoan phylum?
Apicomplexa
Trypanosoma brucei gambiens belongs to which Protozoan phylum?
Euglenozoa
Trypanosoma cruzi belong to which Protozoan phylum?
Euglenozoa
Vaginitis is caused by __________.
Trichomonas vagnalis
Colpitis macularis AKA
strawberry cervix
Colpitis macularis (strawberry cervix) can be caused by ______.
Trichomonas vagnalis
Does Trichomonas vaginalis have a cyst stage?
No
3 Major Features of Archaezoa
- No mitochondria
- Spindle-shaped
- 2+ Flagella @ front end
Rx
prescription
Tx
treatment/therapy
2 Rx frequently used to treat Trichomonas vagnalis
- Metronidazole
- Tindamax
Dx
diagnosis
DDx
differential diagnosis
Giardia lamblia causes _________.
Giardiasis
How does Giardia attach to the intestine?
Adhesive Disk
3 Methods Used to Diagnose Giardia
- Microscopic Inspection of Stool
- Enterotest (string test)
- Small Intestinal Biopsy
(EGD: esophagogastroduodenoscopy)
2 Rx that can be used to treat Giardia
Metronidazole
Tinidazole
2 Rx frequently used to treat Entamoeba histolytica
Metronidazole
Tinidazole
Causes Malaria
Plasmodium spp.
Female mosquitoes are a _______ for malaria.
vector
vector
any arthropod that transmits disease by feeding
shizogony AKA
multiple fission
Malaria destroys RBCs which in turn causes _____.
anemia
What common medicine should not be given to someone with Malaria?
Aspirin
Toxoplasmosis gondii causes ________.
Toxoplasmosis
Why should pregnant women not mess with cat litter or eat undercooked meat?
They may get toxoplasmosis which can cause severe birth defects.
2 Common Ways to Dx Toxoplalsmosis
- Serological Tests
- Fluorescent Antibody (FA) Techniques
2 Rx frequently used to treat Toxoplasmosis
- Pyrimethamine
- Sulfadiazine
Giardia is transmitted by a ___________ Cycle.
Oral-Fecal Cycle
Cyrotpsporidium is transmitted by a ___________ Cycle.
Oral-Fecal Cycle
Cryptosporidium causes _______.
Cryptosporidiosis
2 Major Ways to Dx Cryptosporidium
- PCR
- Microscopy of Stool
Tx of Cryptosporidium
- Rehydration
- Anti-Diarrheal
hemoflagellates
flagellates that live in the blood
Trypanosomiasis AKA
sleeping sickness
Tsetse Flies transmit which disease?
Trypanosomiasis (Sleeping Sickness)
Tsetse Flies are found in which part of the world?
sub-Saharan Africa
CSF
cererbrospinal fluid
Dx of Trypanosomiasis
analysis of serum (blood) or CSF
Stage 1 of Trypanosomiasis
Trypanosoma brucei gamiense travel through the bloodstream & multiples
Stage 2 of Trypanosomiasis
Trypanosoma brucei gamiense crosses the BBB into the CNS
BBB
Blood Brain Barrier
CNS
Central Nervous System
How is Trypanosomiasis Diagnosed?
Analysis of serum of CSF
Chagas Disease AKA
American Trypanosomiasis
Chagas Disease is caused by ______.
Trypanosoma cruzi
Chagas Diseaes is transmitted by which vector?
Triatoma (Kissing Bug)
What are the 2 Stages of Chagas Disease?
- Acute
- Chronic
Rx used to treat Trypanosomias cruzi
nifurtimox
Helminths are Found in Which 2 Major Phyla?
Nematodes (roundworms)
Platyhelminths
(flatworms)
Flatworms AKA
Platyhelminths
Roundworms AKA
Nematodes
3 Types of Nematones (Roundworms)
- Pinworms
- Ascaris
- Trichinella
2 Types of Platyhelminths (Flatworms)
- Trematodes (Flukes)
- Tapeworms
Dioecious
two different sexes
Monoecious
only one sex
each organism is hermaphroditic and has both male and female reproductive parts
Trematode AKA
Fluke
Are Trematodes Dioecious or Monoecious?
Monoecious
(each organism has both ovaries in testes)
How do trematodes eat?
they absorb their food
Cestode AKA
Tapeworm
Causes Taeniasis
Tapeworm
Scolex
head
Two main parts of a tapeworm
scolex (head) & proglottids
each proglottid contains both ____ and ____.
Ovaries & Testes
Taenia saginata AKA
Beef Tapeworm
Where in the human body do Tapeworms live?
lumen of small intestine
How does one get infected with tapeworm?
eating raw/undercooked meat
common symptoms of tapeworm infection
- significant weight loss
- proglottids in feces
- increased appetite
- upset stomach
Enterobius vermicularis AKA
pinworm
enterobius vermicularis causes
enterobiasis
Are pinworms dioecious or monoecious?
dioecious
What is an easy way to look for pinworms?
put a piece of tape over the anus at night to see if any pin worms are stuck to it in the morning
Ascaris lumbricoides causes
Ascariasis
Ascaris lumbricoides AKA
Large Roundworm
Where is Ascaris often found in the body?
GI Tract and associated ducts, lungs, blood, throat, mouth, nose
Why does ascaris often go so long without diagnosis?
oftentimes people are asymptomatic for a long time
Tx for Ascaris
- Mebendazole
- Albendazole
- Surgery
Trichinella spiralis causes
trichinellosis or trichinosis
How does one often get infected by trichinella sprialis?
undercooked meat
Where in the body is trichinella spiralis often found?
Gut, blood, muscle, lungs, brain
How is trichinella spiralis often diagnosed?
muscle biopsy
4 common vectors found in the Arachnid Class
- spiders
- ticks
- mites
- scorpions
3 common vectors found in the Insect Class
- flies
- mosquitoes
- lice
Pediculosis capitis AKA
head lice
nit
lice egg
Phthirus pubis AKA
Crab or Pubic Lice
Pediculus humanus corporis
Body Lice
Pediculosis AKA
lice infection
symptoms of lice
small, itchy, red bumps on the skin
Tx for lice
OTC lotions/shampoos
Size of Lice
1 - 3.5 mm
Dust Mites cause ____ & _____.
Asthma & Allergies
Myiasis
infection of human tissue with maggotslm
maggots
fly larvae
Dermatobia hominis AKA
human bot fly