LATG: Unit 1 Review Flashcards
1
Q
What is an acceptable method of dealing with noncontrolled drugs that are past their expiration date?
A
Label them as “Not for Use in Live Animals.”
2
Q
What best describes “organizing”?
A
establishing a structure
3
Q
What is the purpose of charging a per diem rate?
A
to recover costs associated with animal housing
4
Q
When obtaining animals for research, the purchase order must include what?
A
Species, strain, and number approved by the IACUC in the researcher’s protocol
5
Q
What is the term for the systematic approach to ensuring that various aspects of a laboratory operation meets specified requirements?
A
quality assurance
6
Q
What approach would be the best way to avoid high employee turnover?
A
offer flexible work hours
7
Q
What statement best applies to Good Laboratory Practices regulations?
A
They apply to nonclinical studies for the assessment of the safety of chemicals to humans, animals, and the environment.
8
Q
What determines the selection of a type of respirator?
A
the nature and degree of pulmonary hazard
9
Q
According to Maslow’s hierarchy of needs, giving an employee a promotion would help satisfy which type of need?
A
esteem
10
Q
Regulations and standards for USDA- regulated species are specified in which of the following?
A
Animal Welfare Act
11
Q
What is often referred to as the Worker Right-to-Know legislation?
A
OSHA’s hazard communication standard
12
Q
As a radioactive substance decays, the energy and particles that are emitted are referred to by what?
A
radiation
13
Q
When charging for services by time and materials, how are total labor costs calculated?
A
An hourly rate is multiplied by the number of service hours provided over a period of time..
14
Q
Exposure to what is a potential hazard related to the use of lasers during surgery?
A
Aerosols and gases
15
Q
What type of radiation is electromagnetic radiation generated from radioactive decay?
A
gamma radiation
16
Q
What can the multiplex fluorescent immunoassay detect?
A
presence of viral antibodies
17
Q
What is the most important component of the Hazard Communication Standard (HCS) right-to-know program?
A
employee training and information program
18
Q
What is the most essential component of an effective occupational health and safety program?
A
an adequate risk assessment
19
Q
What must be done if the accounting system categories needed by an animal research facility are not mirrored by the organization’s system?
A
The facility must adapt to the organization’s classifications.
20
Q
In facilities housing nonhuman primates, special considerations must be documented for:
A
animals with restricted activity
21
Q
What is a recommended step you should follow in choosing an animal supplier?
A
Check the vendor’s recent USDA inspection reports for issues.
22
Q
What is the three-step progression followed by many companies in disciplining employees?
A
Verbal warning, then a written warning, and then termination
23
Q
Which statement best describes the intent of the “mirror principle”?
A
Your employees will generally react toward you the way you act toward them.
24
Q
What agency administers the Animal Welfare Act?
A
Animal Plant and Health Inspection Service
25
What is the main advantage of the adhesive plastic tape used to test the effectiveness of cage washers?
Can be kept as a permanent record
26
What is recombinant DNA?
DNA that has been created in a laboratory
27
What is recommended for animals such as genetically engineered rodents obtained from sources other than licensed vendors?
Quarantine them upon arrival.
28
What describes carbon-14 (14C), tritium (3H), and Iodine-125 (125I)?
radioisotopes
29
What must be the basis of any increase in rates?
cost analysis
30
In which phase of the ADDIE instructional design model does the needs assessment take place?
analyze
31
What action must always be done before opening the door of an autoclave?
check the pressure gauge
32
What best describes the "community right-to-know" regulations?
A list of all hazardous materials present in the facility must be made available to local emergency response groups.
33
What must be known to determine if training is the appropriate response to a situation with a procedure in the facility?
root cause of the issue
34
What is one of the main factors that determine the number of sentinels used?
expected morbidity of agents being monitored
35
What should a trainer do before modifying existing training when a compliance issue has just been observed?
consult with management
36
What have some facilities used in place of sound to alert staff regarding a fire in the facility?
red flashing lights
37
What is the overall goal of a good security plan?
To minimize damage and quickly restore a safe and fully functioning environment.
38
Establishing good containment safeguards for general waste helps prevent what?
Objectionable odors and formation of allergenic aerosols
39
What is a basic principle that should be used when staffing a facility?
Divide the workload so that an average person can reasonably accomplish the tasks within the regular working hours.
40
Along with the Nuclear Regulatory Commission, who administers the licensees of nuclear material?
agreement states
41
Recertification at specific intervals is required for what equipment?
Biosafety cabinets located throughout the animal care facility and procedure areas
42
Researchers who work with serum, blood, or tissues from humans or apes should receive what vaccine?
hepatitis B
43
Statistics show that about ____ % of the people who work with laboratory animals develop allergic symptoms.
44
44
What helps to quickly identify that a laminar flow workstation is not a biological safety cabinet?
lack of front window
45
Who is responsible for ensuring that individuals who work inside the facility know what to do in the event that a security breach occurs?
the facility manager
46
Heavy equipment, sharps, and animal bites are considered what type of hazard?
physical
47
Developing a reporting structure can be classified as what kind of activity?
organizing
48
What is generally the best way to ensure that the facility is staffed every day while keeping the budget in check?
Using a rotating weekend and holiday duty system
49
At which level of Maslow's hierarchy of needs would you place providing adequate security in the facility?
safety needs
50
Repairing the facility after a disaster would be considered part of which of the disaster planning steps?
recover
51
What organization accredits research institutions with high-quality programs that meet federal laws and guidelines?
AAALAC, international
52
What method is generally used for disposal of potentially infectious medical waste?
incineration
53
Which article of PPE is most important to wear when mixing caustic detergents?
eye protection
54
How soon after exposure should a sentinel be tested for a specific pathogen?
3-6 weeks after exposure
55
PCR rodent infectious agent (PRIA) testing allows swift identification of environmental pathogens by detecting what?
Pathogen genetic material
56
What ABSL level should be used when working with an agent whose risk of transmission is unknown?
4
57
The highest risk for introducing pathogens into an animal facility is through what?
introduction of live animals
58
What best describes conceptual skills?
the ability to think analytically or creatively
59
What type of sampling can be used in place of bedding sentinels?
environmental dust
60
What is used to represent an estimate of the reasonable level of a chemical to which a worker can be exposed without adverse effects?
Threshold Limit Value
61
How often must the PHS Assurance be resubmitted?
every 5 years
62
Who has the primary responsibility of protecting an animal care technician from exposure to hazards in the animal facility?
the technician
63
What do the "N," "R," and "P" in the description of respirators refer to?
The respirator's filter resistance to oil in aerosol
64
When a report of noncompliance is deemed by OLAW to be a violation of the Animal Welfare Act, who does OLAW inform?
USDA
65
What most accurately describes the Office of Laboratory Animal Welfare?
An NIH office that oversees compliance with the PHS policy
66
What does the National Institutes of Health require of facilities performing research using recombinant DNA?
a biosafety committee
67
What is difference between the Animal Welfare Act and the PHS Policy?
PHS also covers mice, rats and birds
68
Which type of ionizing radiation is best described as small particles that move at high speed and are moderately penetrating?
beta particles
69
Which class of biosafety cabinets offers the most protection to personnel?
III
70
The highest priority in the event of a disaster is:
ensuring the safety of the staff
71
Along with the development and coordination of emergency plans with local community response groups, what else do community right-to-know ordinances require?
a lists of hazardous chemicals and their location
72
The performance standards used for performance appraisals should be:
measurable
73
To be compliant with OLAW, what document should be the basis of the IACUC review of the institution's program for the use and care of animals?
The Guide
74
Which type of radiation is electromagnetic radiation generated non-radioactively?
x-rays
75
Which USDA publication clarifies the intent of the Animal Welfare Act?
Animal Care Policy Manual
76
What should be the IACUC's first step in responding to a report of noncompliance?
identify the underlying cause
77
A formal complaint submitted by the union is called a:
grievance
78
What agency has provided published guidance on compliance with regulations for the use of select agents and toxins?
CDC
79
One way to monitor the effectiveness of the cage washing systems is to use adhesive plastic tape that changes color when exposed to a temperature of:
82 C
80
What organization has developed standards and guidelines to help prevent the transmission of zoonoses through importation of animals?
The Convention on International Trade in Endangered Species
81
Who is responsible for providing security-related training to all staff in an animal facility?
the institution's security personnel
82
What is zoonosis?
An infection that can be transmitted between animals and humans
83
Work with moderate risk agents that are associated with human diseases of varying severity should be performed at what ABSL level?
2
84
What is the purpose of a radiation film badge?
to monitor exposure to radiation over time
85
Who usually establishes the majority of the unit's goals?
upper-level management
86
Levels of light photo intensity above ______ foot- candles can cause retinal damage in some albino animals.
75
87
What is the recommended order of steps in hiring staff?
Developing a job description, recruiting, interviewing, selecting
88
How does the IACUC address the animal and physical plant chapters of the semiannual Program and Facility Review Report it must file with OLAW?
through a semi-annual facility inspection
89
Where should a laboratory animal technologist obtain specific information regarding regulations on the transport of research animals?
The Regulatory Documents
90
Providing each staff member with specific training regarding GLPs is whose responsibility at the institution?
QA
91
What does "Performance standards should be measurable" mean?
There should be an objective way to determine that a task was done adequately.
92
What document states that an animal facility must develop a disaster plan?
The Guide
93
What pinworm infection can be detected by a tape test?
Syphacia
94
Lecture supplemented with hands-on practice is an example of:
blended learning
95
For easy identification of different items in first-aid kits, a system based on _____ has been adopted.
color
96
What differentiates proficient performance of a task with competent performance of the task?
Consistent accuracy and efficiency
97
What is Bremsstrahlung?
An X-ray produced by beta particles when they decelerate
98
What management function most directly affects accomplishment of the mission of the institution and animal care program?
goal setting
99
People in the general community who have learned that research with animals is a valuable endeavor are less likely to:
Support or join animal rights groups
100
To be compliant with OLAW, the IACUC must review the institution's program for the use and care of animals:
every 6 months
101
A postmortem cecal exam is used to detect which species?
Aspiculuris
102
What step should a lab animal facility manager take to ensure that the supplies and equipment purchased meet the needs of the facility?
Justify purchases and educate the purchasing agents regarding the work and needs within the facility.
103
The ability to clearly relate the facility's goals to the staff is an example of:
communication skills
104
According to Federal law, which controlled substances must DEA registrants store in a securely locked cabinet?
Schedules II-IV
105
What term best describes the methods used to detect adventitious bacteria, viruses, or parasites at an early stage of infection?
Health Surveillance
106
What best describes controlled substances?
drugs that have the potential to become addictive
107
What is an advantage of using decentralized laboratory animal facilities?
They are generally more convenient for the researchers.
108
Technology using adenosine triphosphate (ATP) test swabs uses _______ to measure organic residue.
light
109
A substance that is classified as a Schedule I controlled substance has _____________ potential for addiction than one that is in Schedule III.
greater
110
What agency is responsible for issuing permits for importing or exporting wild species?
The US Fish and Wildlife Service (FWS)
111
Regular backup of important files would be considered part of which disaster planning step?
mitigate
112
How many days does it generally take for an animal to develop an immune response to an agent?
10-14
113
All staff should be trained in __________ and _______________as part of a general disaster plan.
the use of fire extinguishers; basic first aid
114
What purpose do subsidies serve?
reduce costs to run the facility
115
What is the concern when disposing of bedding from healthy animals?
allergenic aerosols
116
Demonstrating compliance can be achieved how?
good recordkeeping
117
Thick dense shielding must be used to protect a worker from which type of radiation?
gamma radiation and x-rays
118
What is a good approach to inventory control?
Keep a good balance between what is bought and what is used.
119
What institutional office generally has the responsibility for monitoring the handling of radioactive materials in the laboratory?
Radiation Safety Officer
120
Who is typically responsible for space management in a facility?
The manager in collaboration with the veterinarians and senior scientific staff
121
Animals that are kept under conditions similar to those of the experimental animals and are used to document the health status of the colony are known as:
sentinels
122
What type of bedding is required in GLP studies?
certified
123
How many schedules of controlled substances are there?
5
124
A verification of what has been learned is the definition of which term?
assessment
125
What provides standards for the humane transport of laboratory animals?
Animal Welfare Act
126
What is blended learning?
learning from 2 or more training modalities
127
How often should a research facility using regulated species update their USDA registration?
every 3 years
128
What protective item is required in facilities housing aquatic species?
GFCI outlets
129
What is certified feed?
The concentration of contaminants is below maximum acceptable levels.
130
What is specified by the different Hazard Communication Standard pictograms on chemical labels?
the type of hazard
131
What is a good reference for those who are responsible for managing controlled substances?
DEA Practitioner's Manual
132
What is a common method used to detect exposure to viral pathogens?
ELISA
133
What method of reporting an incident is most likely to lessen consequences from funding or regulatory agencies?
self-reporting
134
What best describes the skill of organizing?
establishing a structure
135
What can make workload allocation successful?
organize workload to using good management principles, communicate to the staff the reasons behind the workload allocation, monitor to determine how well the workload division meets the needs of the unit
136
In what level of Maslow's hierarchy of needs would you place by giving an employee a plaque to recognize exceptional performance?
esteem needs
137
What is generally the best way to ensure that the facility is staffed everyday while keeping the budget in check?
use a rotating holiday and weekend schedule
138
What is the first step in developing training project using the ADDIE model for training?
Analyze
139
The ability to preform a procedure to an acceptable standard is:
competency
140
A good approach to inventory control is:
keep a good balance between what is bough and what is used
141
How are per diem rates set to recover costs associated with animal housing?
dividing the accumulated costs be the total units of service
142
When preparing a budget, what is the most accurate starting point for planning expenses?
expenses for the previous year
143
What option for adding animal housing space generally has the lowest construction cost?
using a prefabricated modular facility
144
In a large facility, who generally coordinates the purchase of animals?
the centralized veterinary service department
145
What is an element of a facility evaluation to determine what types of disasters could affect the animal facility?
location
146
Installing emergency equipment would be considered which part of the disaster planning steps?
prepare
147
What is the number one priority in an emergency?
the safety of the staff
148
All staff should be trained in __________ and __________ as part of a general disaster plan.
the use of fire extinguishers and basic first aid
149
What regulatory agencies codify GLPs for laboratory studies?
FDA, EPA, OECD
150
What best describes AALAC's program status evaluation?
confidential peer review process
151
What document provides standards for the humane transportation of laboratory animals?
The AWA Regulations
152
What organism can be detected by an anal tape test?
Syphacia
153
When monitoring effectiveness of the autoclave cycle, where should the envelope containing paper strips or plastic vials of spores be placed?
in the middle of the densest, largest load
154
What is the main goal of maintaining sentinels in animal rooms?
to allow detection of pathogens affecting the animal facility
155
What is the first step in developing an occupational health and safety program?
identify types of hazards in facility
156
What is the main goal of maintaining sentinels in an animal room?
to detect pathogens affecting the colony
157
What is the typical profile of someone who develops a laboratory animal allergy?
worker in their 20 with less than 3 years of occupational contact and allergies to plants or foods
158
What is used to represent an estimate of the reasonable level of a chemical to which a worker can be exposed without adverse effects?
Threshold Limit Value
159
What ABSL level should be used when working with an agent whose risk of transmission is unknown?
4
160
What is the best way to protect the technician from exposure to aerosolized infectious agents?
performing the work in a Class III BSC
161
Heavy particles that travel only a few centimeters in the air best describes what type of ionizing radiation?
alpha particles
