LATG Final Review Flashcards
1
Q
What is a major advantage of fluoroscopy over standard radiography?
A
it takes moving pictures
2
Q
Continuous exposure to acoustical levels above what level can have both auditory and non-auditory effects?
A
85 db
3
Q
What method is used to diagnose coccidiosis in rabbits?
A
fecal float
4
Q
What is a serious complication associated with the use of the anesthetic tribromoethanol?
A
intestinal ileus
5
Q
What cell type is a component of the innate immune system?
A
Phagocytes
6
Q
What purpose do subsidies serve?
A
To reduce costs to run the facility
7
Q
What is the term used to describe an animal with a normal immune system?
A
immunocompetent
8
Q
Which type of radiation is electromagnetic radiation generated from radioactive decay?
A
gamma radiation
9
Q
Thick dense shielding must be used to protect a worker from what type of radiation?
A
gamma radiation and x-rays
10
Q
What is the product of replication?
A
DNA
11
Q
Who usually establishes the majority of the unit’s goals?
A
upper-level management
12
Q
Along with the development and coordination of emergency plans with local community response groups, what else do community right-to-know ordinances require?
A
A list of hazardous chemicals and their location
13
Q
What is an appropriate starting point for preparing a budget of expenses for the next fiscal year?
A
the amount of money spent in the previous fiscal year
14
Q
Which agency administers the Animal Welfare Act?
A
APHIS
15
Q
What should be used to clear Clostridium pilliforme from equipment?
A
An antisporicidal sterilant
16
Q
Heavy equipment, sharps, and animal bites are considered what type of hazard?
A
physical
17
Q
Which zoonotic viral disease often remains asymptomatic in infected macaques and can be fatal in humans?
A
B virus
18
Q
Which imaging technique uses a radioisotope to provide images of in vivo biological processes?
A
Positron emission tomography
19
Q
What document states that an animal facility must develop a disaster plan?
A
The Guide
20
Q
What best describes a congenic strain?
A
The result of backcrossing for 10 generations
21
Q
What is the term for a molecule that is composed of a series of chemical subunits which are linked together?
A
polymer
22
Q
What group of worms are generally elongate, cylindrical, and non-segmented?
A
nematodes
23
Q
_______ allows lipids to be absorbed through the wall of the small intestine and used as energy in the body.
A
bile
24
Q
Hemoglobin is the:
A
oxygen carrying component of RBCs
25
To reduce the chance of contracting orf, what precaution should always be taken by personnel handling sheep?
wear gloves
26
What ABSL level should be used when working with an agent whose risk of transmission is unknown?
4
27
What do the "N," "R," and "P" in the description of respirators refer to?
The respirator's filter resistance to oil in aerosol
28
Animals that have a normal intestinal flora but are free of particular organisms are called:
specific pathogen free
29
If a transgene is integrated in one of the chromosomes of a pair, the animal is said to be:
hemizygous
30
The roles of cell-to-cell communication and self-recognition by the immune system are fulfilled by:
glycoproteins
31
A bacterial septicemia that occurs frequently in frogs and that can cause erosion of the toes, feet, and jaws is called:
red leg
32
What does an ultrasonic Doppler flow detector measure?
blood pressure
33
What differentiates proficient performance of a task with competent performance of the task?
consistent accuracy and efficiency
34
Statistical analysis is used to:
draw conclusions based on the data from a study.
35
What is the tell-tale sign of a pregnant mouse?
budging abdomen
36
Mycobacteriosis in fish is thought to spread through what?
cannibalism of tank mates
37
What is the concern when disposing of bedding from healthy animals?
allergenic aerosols
38
What biomolecule carries the cell's genetic information across the nuclear membrane?
mRNA
39
What type of radiation is electromagnetic radiation generated non-radioactively?
X-rays
40
In protein synthesis, during which step is messenger RNA formed?
transcription of DNA
41
A white blood cell differential is also known as a:
leukogram
42
If a genetically modified mouse is dying and cannot be saved, it is important to attempt to save which of the following?
gonads
43
How does the IACUC address the animal and physical plant chapters of the semiannual Program and Facility Review Report it must file with OLAW?
semi-annual investigation
44
Which organelle uses information contained in the mRNA to connect amino acids and form a protein?
Ribosome
45
Organic acids consisting of a chain of hydrocarbons are __________.
fatty acids
46
What is the primary sign of orf?
blisters
47
What disease is characterized by fish rubbing their sides and flipping around in the corners of the tank?
velvet disease
48
Using Western blot, what enables visualization of the protein?
antibodies
49
For which purpose does the transfer sleeve of an isolator have nipples?
sterilant injection
50
What is blended learning?
learning from 2 or more training modalities
51
In rebreathing systems, the exhaled gases pass through a canister that absorbs what?
carbon dioxide
52
What describes carbon-14 (14C), tritium (3H), and Iodine-125 (125I)?
radioisotopes
53
A verification of what has been learned is the definition of which term?
assessment
54
Which USDA publication clarifies the intent of the Animal Welfare Act?
Animal Care Policy Manual
55
What term is used for the quantity of the drug per unit of body weight?
dose rate
56
What is the product of translation?
Protein
57
________ helps to eliminate personal bias from a study and to allow the independent variable to control.
Randomization
58
What is the stage when a protozoan parasite actively multiplies?
Trophozoite
59
What is the causative agent of Tyzzer's disease?
Clostridium piliforme
60
Otitis externa in cats may be associated with infestation by what arthropod?
Notoedres cati
61
In which phase of the ADDIE instructional design model does the needs assessment take place?
analyze
62
What is the term for the solid media used to grow bacteria?
agar
63
If you are anesthetizing a 5 kg dog using a rebreathing system, what capacity would you choose for the rebreathing bag?
600ml
64
Toxocara canis is which type of parasite?
ascarid
65
In which group of helminths are tapeworms found?
cestodes
66
What disease causes lethargy and excessive mucus and white spots on the skin of fish?
ich
67
An imbalance in the different types of lipoproteins (HDL versus LDL) is a major contributing factor in what disease?
Atherosclerosis
68
What method of reporting an incident is most likely to lessen consequences from funding or regulatory agencies?
self-report
69
Technology using adenosine triphosphate (ATP) test swabs uses _______ to measure organic residue.
light
70
When a report of noncompliance is deemed by OLAW to be a violation of the Animal Welfare Act, who does OLAW inform?
USDA
71
What symptoms are characteristic of microsporidiosis in fish?
Emaciation and spinal curvature
72
The first step in developing a disaster plan should be to:
identify the types of disasters which might affect the facility.
73
What is the overall goal of a good security plan?
To minimize damage and quickly restore a safe and fully functioning environment.
74
When wild type females are bred to hemizygous males, what percentage of the resulting pups can be expected to have the transgene?
50%
75
Radioactive isotopes can be attached to which molecule in positron emission tomograph?
glucose
76
What is used to represent an estimate of the reasonable level of a chemical to which a worker can be exposed without adverse effects?
threshold limit value
77
At which level of Maslow's hierarchy of needs would you place providing adequate security in the facility?
safety needs
78
What disease in fish can be successfully treated with repeated dilute formalin baths?
Ich
79
What is recommended for animals such as genetically engineered rodents obtained from sources other than licensed vendors?
Quarantine upon arrival
80
What must be the basis of any increase in rates?
cost analysis
81
In which room access type are primary investigators allowed to conduct some manipulations, although facility personnel have the majority of contact with the animals?
limited access
82
What management function most directly affects accomplishment of the mission of the institution and animal care program?
goal setting
83
What component of the innate immune system coats the surface of invading organisms to facilitate their attack by the macrophages?
complement proteins
84
Cannibalism of new pups is a frequent problem in which mouse strain?
C57BL/6
85
How would you classify the athymic mouse's immunodeficiency?
a primary immunodeficiency disease
86
In what species does the administration of morphine frequently induce vomiting and defecation?
dogs
87
Ringworm is an example of what?
Cutaneous mycosis
88
What do high concentrations of neutrophils usually indicate?
active bacterial infection
89
How often should a research facility using regulated species update their USDA registration?
every 3 years
90
Blood types are characterized by the carbohydrate portions of _______ on the surface of cells and the carbohydrate portion of serum _______.
glycolipids, glycoproteins
91
What term refers to the thousands of microbial species that inhabit a specific host?
microbiome
92
Providing each staff member with specific training regarding GLPs is whose responsibility at the institution?
QA unit
93
If swine are unable to access water, they may develop:
salt toxicity
94
A good way to screen the health status of incoming animals is to:
request several extra animals from the vendor to use for health screening.
95
What best describes genetic engineering?
Manipulating DNA molecules to alter their composition
96
Using the pronuclear injection technique, what is the average percentage of offspring carrying the transgene?
20%
97
A nonrebreathing system is used for animals of what weight range?
less than 5kg
98
What is typical of a secondary (anamnestic) immune response?
The serum titer rises to a higher level than during the primary response.
99
Guinea pigs housed on wire floors may have inflamed, swollen, and painful feet due to infection with what organism?
Staphylococcus aureus
100
Carbohydrates made up of two monosaccharides are classified as:
Disaccharides
101
Which carbohydrate is the primary source of energy used for metabolic processes?
glucose
102
What are hydatid cysts?
Fluid-filled cyst containing tapeworm larvae
103
What breaks down dietary fiber?
bacteria
104
What represents a difference between the Animal Welfare Act and the PHS Policy?
PHS Policy covers mice, rats, and birds.
105
What does a pulse oximeter measure?
level of oxygen in blood
106
Heating devices used to maintain the body temperature of anesthetized animals should be ___________ the animal's normal body temperature.
1-2 degrees higher than
107
Bacteria that can grow in the absence of oxygen are known by what term?
anaerobic
108
What are the three steps involved in an acquired immunity response to a foreign substance?
Recognition, amplification, and resolution
109
What best defines the term “variable” as used in the biomedical research field?
It represents anything that can affect the results of a study.
110
What tissue type is used to test for mouse parvovirus?
lymph node
111
Under which condition will viruses grow?
cell culture
112
What is the tidal volume for most laboratory animals?
15-20ml/kg
113
A mycelium is formed by what?
A mold colony
114
What antibiotics are preferred to treat enteric coccidiosis?
Sulfonamides
115
What information is gained from continuous monitoring of blood pressure?
cardiac output
116
Post-anesthetic behavioral changes can persist for up to ___ hours in animals administered dissociative anesthetics.
24
117
What carbohydrate serves as energy storage in animals?
glycogen
118
Helicobacter spp. are most commonly diagnosed with what technique?
PCR
119
What is one precaution that must be considered when using urethane as an anesthetic agent?
It must be used with protective equipment.
120
For what condition are cephalosporins often used?
Conditions that have shown resistance to other antibiotics
121
To prevent ruminants from suffering positional bloat during a surgical procedure, what measure is typically taken during the procedure?
placement of rumen tube
122
Cats are the definitive host of which species of apicomplexan parasite?
Toxoplasma gondi
123
What is the most important component of the Hazard Communication Standard (HCS) right-to-know program?
employee training
