Kinetics

Question 1

What is rate?

Answer 1

How fast reactions are being consumed or how fast products are formed

Question 2

What is reactant rate determined by?

Answer 2

How frequent reactant molecules collide, orientation of colliding molecules, and energy

Question 3

When does transition state usually occur?

Answer 3

At the energy max

Question 4

Are kinetic and thermodynamic factors related?

Answer 4

No

Question 5

What does a catalyst do?

Answer 5

Accelerates the reaction by lowering activation energy

Question 6

Do catalyst effect equilibrium?

Answer 6

No

Question 7

What order is the rate for a unimolecular step?

Answer 7

First order

Question 8

What order is the rate for the bimolecular step?

Answer 8

Second order

Question 9

What will adding a catalyst or increasing temperature do to the rate constant?

Answer 9

Increase the rate constant

Question 10

What is kcat?

Answer 10

Number of substrate molecules converted to product per unit time. Limiting rate at saturation

Question 11

Effects of uncompetitive inhibition

Answer 11

Only binds to enzyme substrate complex. Lowers Vmax. LWB shows parallel lines. As inhibitor is increased lines shift to the left

Question 12

Effects of mixed inhibition

Answer 12

Binds to enzyme or enzyme substrate complex. Vmax goes down. Km goes up. LWB shows intersection

Question 13

Effects of competitive inhibitor

Answer 13

Vmax has no change but km will