Influenza Flashcards
1
Q
Signs and Symptoms for Influenza
A
- Sudden fever
- Pharyngitis
- Congestion
- Cough
- Tiredness
- Pale
- Muscle ache
2
Q
Causative agents for Influenza
A
Influenza virus types A and B
- Envelope virus
- RNA virus
3
Q
What are the two main causes for mutations in Influenza?
A
- Antigenic drift
- Antigenic shift
- ^^ cause multiple strains
4
Q
Pathogenesis for Influenza
A
- Produced immune response to the virus
- Flu patients are susceptible to secondary bacterial infections
5
Q
Epidemiology for Influenza
A
- Complications in the elderly, children, and those with chronic diseases
- 2009 H1N1 variants bound lower in respiratory tract causing massive cytokine storm
6
Q
Diagnosis for Influenza
A
- Signs and symptoms
- Often diagnostic
7
Q
Treatment for Influenza
A
- Four drugs approved
- Take during the first 48 hours
- Supportive care
- Antiviral (early on)
8
Q
Prevention for Influenza
A
- Immunization
- Multivalent vaccine
- IgG/ flu vaccination (works 10%)
9
Q
Pathogenesis and Virulence Factors for Influenza
A
- Virus binds ciliated cells of the respiratory mucosa
- Severe inflammation, irritation in lungs due to “cytokine storm”
10
Q
Culture for Influenza
A
- Culture and non-culture based tests
- Rapid influenza tests:
- Immunofluorescence
- PCR
- ELISA
- Viral culture
11
Q
If not treated?
A
Pneumonia (most likely if really young or really old)
12
Q
Transitions fr Influenza
A
Transmitted via inhalation of airborne viruses or by self-inoculation
