Genital Ulcer Diseases/Syphilis Flashcards

1
Q

Three common infectious conditions can result in lesions on the genitals

A
  • Syphilis
  • Chancroid
  • Genital herpes
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2
Q

What other causes can Genital Ulcer have?

A

HIV because of open lesions

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3
Q

Syphilis Signs and Symptoms

1&2

A
  1. Chancre (painless, hard lesion) “Chancre”

2. Rash, sore throat, headache, mild fever, malaise, myalgia

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4
Q

Syphilis Signs and Symptoms 3&4

A
  1. Latent- no clinical signs

4. Gummas, dementia, blindness, paralysis, heart failure

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5
Q

Pathogen and Virulence Factors for Syphilis

A

Narrow spirochetes difficult to be seen by regular light microscope

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6
Q

Causative agent for Syphilis

A

Treponema pallidum

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7
Q

Pathogenesis

Transmission for Syphilis

A
  • Sexual contact
  • Mother to fetus cause
  • death
  • retardation
  • malformation
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8
Q

Susceptibility for Syphilis

A

Sexually active individuals

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9
Q

Diagnosis for Syphilis

A
  • Primary, secondary, and congenital

- Antibody test against T. pallidum antigens

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10
Q

Treatment for Syphilis

A

Primarily with penicillin G

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11
Q

Prevention for Syphilis

A
  • Abstinence
  • Mutual monogamy
  • Condoms
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