Infecciones ginecológicas Flashcards

1
Q

pH vaginal normal

A

4-4.5

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2
Q

Bacterias que aumentan crecimiento en vaginosis bacteriana

A

Gardnerella vaginalis, Ureaplasma urealyticum, Mobiluncus species, Mycoplasma hominis, and Prevotella species

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2
Q

Bacterias que aumentan crecimiento en vaginosis bacteriana

A

Gardnerella vaginalis, Ureaplasma urealyticum, Mobiluncus species, Mycoplasma hominis, and Prevotella species

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3
Q

Células características en vaginosis bacteriana

A

células diana (clue cells) 20%

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4
Q

Esquema de tx de vaginosis bacteriana

A

Recommended regimens
Metronidazole (Flagyl) 500 mg orally twice daily for 7 days
Metronidazole gel 0.75% (Metrogel vaginal) 5 g (1 full applicator) intravaginally once daily for 5 days
Clindamycin creama 2% (Cleocin, Clindesse) 5 g (1 full applicator) intravaginally at bedtime for 7 days

Alternative regimens
Tinidazole (Tindamax) 2 g orally once daily for 2 days
Clindamycin 1 g orally once daily for 5 days
Clindamycin ovulesa (Cleocin)100 mg intravaginally at bedtime for 3 days

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5
Q

Estados de lesiones de HSV

A

(1) vesicle with or without pustule
formation, which lasts approximately a week; (2) ulceration; and (3) crusting.

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6
Q

Estados de lesiones de HSV

A

(1) vesicle with or without pustule
formation, which lasts approximately a week; (2) ulceration; and (3) crusting.

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7
Q

Gold standard para el dx de HSV

A

gold standard or the diagnosis o genital herpes is tissue culture.

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8
Q

Tx HSV

A

First clinical episode
Acyclovir 400 mg three times daily for 7–10 days
Famciclovir (Famvir) 250 mg three times daily for 7–10 days
Valacyclovir (Valtrex) 1 g twice daily for 7–10 days

Episodic therapy for recurrent disease
Acyclovir 400 mg three times daily for 5 days
Famciclovir 125 mg twice daily for 5 days
Valacyclovir 500 mg twice daily for 3 days

Suppressive therapy
Acyclovir 400 mg twice daily

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9
Q

Estados de sífilis

A

Primary syphilis, the hallmark lesion is the chancre, in which spirochetes are abundant. Nontender ulcer.

Secondary syphilis, bacteremia develops 6 weeks to 6 months a ter a chancre appears. Its hallmark is a maculo-papular rash that may involve the entire body and includes the palms, soles, and mucous membranes. As is true or the chancre, this rash actively sheds spirochetes. With highly infectious plaques called condylomata lata.

Tertiary syphilis is the phase o untreated syphilis that may appear up to 20 years after latency. During this phase, cardiovascular, CNS, and musculoskeletal involvement become apparent

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10
Q

Esquema de tx de sífilis

A

Primary, secondary, early latent (< 1 year) syphilis
Recommended regimen:
Benzathine penicillin G, 2.4 million units IM once Alternative oral regimens (penicillin-allergic,
nonpregnant women): Doxycycline 100 mg orally twice daily for 2 weeks

Late latent, tertiary, and cardiovascular syphilis
Recommended regimen:
Benzathine penicillin G, 2.4 million units IM weekly times
3 doses
Alternative oral regimen (penicillin-allergic, nonpregnant
women): Doxycycline 100 mg orally twice daily for 4 weeks

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11
Q

Tratamiento chancroide

A

regimens or nonpregnant women include single doses o oral azithromy- cin (1 g) or IM ceftriaxone (250 mg).
Multiple-dose options are ciprofloxacin 500 mg orally twice daily or 3 days of erythromycin base 500 mg orally three times daily or 7 days.

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12
Q

Diagnóstico de granuloma inguinal

A

Diagnosis by identication of Donovan bodies during microscopic evaluation of a specimen following Wright- Giemsa staining.

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13
Q

Tratamiento de granuloma inguinal

A

Recommended regimen
Azithromycin (Zithromax) 1 g once weekly for at least 3 weeks and until lesions are completely healed
Alternative regimens
Doxycycline 100 mg twice daily as above

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14
Q

Serotipos en linfogranuloma venéreo

A

L1, L2 L3

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15
Q

Estados de linfogranuloma venéreo

A

three stages: (1) small vesicle or papule, (2) inguinal or emoral lymphadenopathy, and (3) anogeni- torectal syndrome.

15
Q

Estados de linfogranuloma venéreo

A

three stages: (1) small vesicle or papule, (2) inguinal or emoral lymphadenopathy, and (3) anogeni- torectal syndrome.

16
Q

Tx de linfogranuloma venéreo

A

doxycycline,100 mg orally twice daily for 21days

17
Q

Definición de candidiasis recurrente

A

4 eventos o más al año

18
Q

Tx de candidiasis recurrente

A

For recurrent C albicans disease, local intravaginal therapy or 7 to 14 days or oral uconazole (Di ucan) in 100-mg,
150-mg, or 200-mg doses once every third day or a total o three doses (day 1, 4, and 7) are options. Suppressive main- tenance regimen or recurrence prevention is oral uconazole, 100 to 200 mg weekly or 6 months.
Non-albicans candidal species are not as responsive to topical azole therapy. For non- albicans recurrent infection, a 600-mg boric acid gelatin capsule intravaginally daily or 2 weeks has been success ul.

19
Q

Tx trichomoniasis normal y resistente

A

metronidazole 2 g once or tinidazole 2 g once
resistente: oral tinidazole at doses o 500 mg orally three times daily or 7 days or our times daily or 14 days

20
Q

Tx de gonorrea normal y alergia a cefalosporinas

A

ceftriaxone 250 mg IM + azithromycin 1 g orally once
gemifloxacin 320 mg plus azithromycin 2 g

21
Q

Tx de clamidia

A

Azithromycin 1 g once
Doxycycline 100 mg twice daily for 7 days

22
Q

Tratamiento de Mycoplasma genitalum

A

azithromycin 1 g orally once is recommended.

23
Q

Organismos asociados a EPI

A

N gonorrhoeae, C trachomatis, T vaginalis.

24
Q

Diagnóstico de EPI

A

uterine tenderness, adnexal tenderness, or cervical motion tenderness is present. One or more o the following enhances diagnostic specicity: (1) oral temperature > 38.3°C (101.6°F), (2) mucopurulent cervical discharge or cervical friability, (3) abundant WBCs on saline microscopy o cervical secretions, (4) elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP), and (5) presence cervical N gonorrhoeae or C trachomatis.

25
Q

Hallazgos us EPI

A

1) trompa de forma ovoide y distendida llena de líquido anecoico o ecógeno; 2) engrosamiento de la trompa de Falopio; 3) tabiques internos incompletos, y 4) aspecto de “rueda dentada” de las trompas inflamadas cuando se les estudia en corte transversal

26
Q

Hallazgos de ATO

A

afected women display signs o PID and a concurrent adnexal or cul-de-sac mass. Sonographically, with OA, a complex cystic adnexal or cul-de-sac mass with thick irregular walls, areas o mixed echogenicity, septations, and
internal echoes rom debris is seen

27
Q

Tx iv de EPI

A

Cefotetan (Cefotan) 2 g IVevery 12 hr or
Cefoxitin (Mefoxin) 2 g IVevery 6 hr PLUS
Doxycycline 100 mg orally or IVevery 12 hr

Clindamycin 900 mg IVevery 8 hr
PLUS
Gentamicin loading dose 2 mg/kg IVor IMfollowed
by a maintenance dose of 1.5 mg/kg every 8 hr. Single daily dosing at 3 to 5 mg/kg per day may be substituted.

Alternative regimen
Ampicillin/sulbactam (Unasyn) 3 g IVevery 6 hr PLUS
Doxycycline 100 mg orally or IVas above

28
Q

Casos en los que se debe de retirar un DIU por EPI

A

enfermedad grave
no mejoría después de 48-72 horas

29
Q

Indicaciones de tx parenteral

A

Pregnant
Adolescents
Drug addicts
Severe disease
Suspected abscess
Uncertain diagnosis
Generalized peritonitis
Temperature > 38.3°C
Failed outpatient therapy
Recent intrauterine instrumentation
White blood cell count > 15,000/mm3 Nausea/vomiting precluding oral therapy

30
Q

Tx ambulatorio de EPI

A

Ceftriaxone (Rocephin) 250 mg IM oncea,b
PLUS
Doxycycline 100 mg orally twice daily for 14 days with or without
Metronidazole (Flagyl) 500 mg orally twice daily for 14 days

31
Q

Sitios más frecuentes de escabiasis

A

hands, wrist, elbows, groin, and ankles

32
Q

Principal manejo de absceso de glándula de Bartolino

A

drenaje

33
Q

Criterios de dx de síndrome de shock tóxico

A

** To meet the strict criteria, a woman must have all major and at least three minor criteria.
Major criteria
Hypotension
Orthostatic syncope
Systolic BP < 90 mm Hg for adults
Diffuse macular erythroderma
Temperature ≥ 38.8°C
Late skin desquamation, particularly on hands, palms, and soles (1–2 weeks later)

Minor criteria (organ system involvement)
Gastrointestinal: diarrhea or vomiting
Mucous membranes: oral, pharyngeal, conjunctival, and/or vaginal erythema
Muscular: myalgia or creatinine level greater than twice normal
Renal: BUN and creatinine greater than twice normal or > 5 WBCs/hpf in urine, without concurrent UTI Hematologic: platelet count < 100,000 per mm3
Hepatic: SGOT, SGPT, and/or bilirubin levels greater than twice normal
Central nervous system: altered consciousness without focal localizing signs

34
Q

Clasificación de infecciones de heridas qx

A

Superficial incisional
Deep incisional
Organ/space

35
Q

Clasificación de infecciones de heridas qx

A

Superficial incisional
Deep incisional
Organ/space

36
Q

Manejo de absceso de glándula de Bartolino

A

drenaje