Host Responses to Viral Infections Flashcards
1
Q
What are the effects retroviruses typically have on cells?
A
Virions get expelled from the cell by budding and the cell does not die
2
Q
Permissive cells are cells that ___________.
A
are able to produce new virions
3
Q
List the three anti-viral properties of IFNalpha and IFNbeta.
A
Activation of NK cells; upregulation of MHC I; and induced resistance to viral replication
4
Q
What kinase mediates the anti-translational state induced by interferon alpha and beta?
A
Protein kinase R
5
Q
What substance, induced by IFNalpha/beta activation, initiates mRNA degradation?
A
Oligoadenylate synthesis
