Exam 2 Miscellaneous Flashcards
Coagulative necroses are seen in ______.
heart myocytes
Liquefactive necroses are seen in ______.
brain and spleen
______ does not protect against reactive oxygen species, but glutathione peroxidase, catalase, and superoxide dismutase do.
Xanthine peroxidase
Does platelet activating factor have systemic effects?
No
Factor XII manifests with pain because ________.
it activates kallikrein which in turn converts kinin to bradykinin
Factor XII activates _____.
C5
What does granulation tissue do?
It lays down the framework on which new epithelium can be laid, but it does not re-epithelialize.
I-CAM helps ________.
leukocytes migrate into tissues
Selectins help ______, while integrins help ______.
in rolling; in adhesion
Fibroblast proliferation, macrophages, and neo-vascularization would be seen in ______.
granulation tissue
What makes D-dimer levels increase?
Breakdown of fibrin in clotting
Red infarctions typically affect ________.
loose tissues (like the lungs or testis), tissues with multiple blood supplies, and tissues with obstructed venous outflow
Snail, twist, and Zeb 1/2 are ______.
transcriptional repressors of E-cadherin
Anti-topoisomerase agents work by ______.
DNA double stranded breaks
Prostate cancer usually occurs in the _____.
periphery of the prostate
The type of lung cancer that is least associated with smoking is _____.
bronchioalveolar carcinoma
Cytotoxic agents can ________.
target a specific enzyme, but targeted agents hit specific enzymes that are faulty in cancer cells only
A cancer that has invaded regional lymph nodes but not metastasized is _____.
stage III
Tumors in the ascending colon typically _____.
protrude into the lumen
List the causes of cancer death from most to least frequent.
Infection, organ failure, thromboembolism, hemorrhage, emaciation
Aspiring overdoses involve ______.
rashes, hepatomegaly, and somnolence
What adhesion molecule normally expressed on T lymphocytes is co-opted by tumor cells?
CD44
Polyaromatic hydrocarbons metabolize to ______.
epoxides
_______ is a definitive pathologic sign of alcoholic hepatitis.
Alcoholic hyaline
Cortisol is ____ acting.
short
Amoeboid movement occurs _________.
quickly via collagen fibers
