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MCQ 1.1 > Hep B/immunology > Flashcards

Hep B/immunology Flashcards

1
Q

If someone presents with Hep B what will be found in the blood

A

AgS surface antigen
AgC core antigen
AgSAb surface antibody
AgCAb core antibody

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2
Q

If someone has natural immunity to Hep B what will be found in the blood

A

AgSAb surface antibody
AgCAb core antibody

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3
Q

If someone has artificial immunity from Hep B what will be found in the blood

A

AgSAb surface antibody

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4
Q

What are examples of mechanical defences

A

Lysozyme - tears
Skin
pH levels
Gut acid
Bronchi mucus cilia
Flushing of urinary tract
Coughing
Sneezing

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5
Q

How do viruses cause disease

A

Attach to the host cell
Penetrate the host cell
Uncoat
Replicate inside the host cell
Assemble
Release

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6
Q

What is an antigen

A

A virus substance which causes the immune system to produce antibodies

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7
Q

What are antibodies

A

The host proteins which protect from unwanted substances

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8
Q

Name 3 lymphocytes

A

B cell
T cell
Large granular lymphocyte

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9
Q

Name 3 phagocytes

A

Mononuclear phagocyte
Neutrophil
Eosinophil

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10
Q

What soluble mediator do B cells create

A

Antibodies

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11
Q

What soluble mediator do T cells create

A

Cytokines

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12
Q

What soluble mediator do large granular lymphocytes create

A

Cytokines

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13
Q

What soluble mediator do mononuclear phagocytes create

A

Cytokines and complement

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14
Q

What is phagocytosis

A

Specialist cells which engulf bacteria and break them down in special compartments containing enzymes and toxic free radicals

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15
Q

What is opsonisation

A

Helps phagocytic cells to pick up the bacteria

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16
Q

What is neutralisation

A

Stops bacteria from binding and colonising the tissue

17
Q

What is inflammation

A

Recruits other cells to the site of infection to help

18
Q

What are the primary immune response organs

A

Bone marrow
Thymus

19
Q

What are the secondary immune response organs

A

Lymph nodes
Spleen
Lymphoid tissues

20
Q

What are the cellular immune response

A

Leukocytes

21
Q

What are the soluble immune responses

A

Antibodies
Complement
Messenger molecules
Anti viral proteins

22
Q

What is an innate response

A

Quick reaction

23
Q

What is an adaptive response

A

Slow reaction but quicker with secondary exposure

24
Q

What is HBeAG

A

In serum indicates active infection and high transmissibility

25
Q

How long does IgG last

26
Q

What links to the Hep B core antibody

A

IgM and IgG

27
Q

What are the two formats for a vaccine

A

Plasma derived
Recombinant DNA

28
Q

Where are B-cells found

A

In the bone marrow

29
Q

Where are T - cells found

A

In lymph cells

MCQ 1.1 (43 decks)

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