Hematopoiesis Flashcards
Formed Elements in Blood
PIC
Hematopoiesis in Fetus
Ontogeny follows phylogeny
Phylogeny of Lymphoid Tissues in Vertebrates
PIC
Bone Marrow can be taken from bones to be tested for cancer– taken from where?
In Babies:
Shaft of Tibia
Adults:
Sternum, Vertebrae, Iliac Spine (Anterior/Superior)
Hematopoiesis
Process of blood cell production
Hematopoiesis: Hemocytoblast
Pluripotential stem cell-common precursor to all blood cell types
Hematopoiesis: Myeloid Stem Cell
Multipotential lineages-capable of self renewal
Hematopoiesis: megakaryocyte
form platelets/thrombocytes fragments of megakaryocytes
Hematopoiesis: monocytes
monocytes that leave blood become macrophages
Hematopoiesis: Lymphoid Stem Cells
multipotential lineages capable of self renewal
-Lymphocytes
T Lymphocytes: Cellular immunity
B Lymphocytes: Humoral Immunity
Red Bone Marrow
is active. Hematogenous (young)
Yellow Blood Marrow
Adipose cells (older) Has been replaced with fat cells
Vascularity of Bone Marrow
PIC
Hematopoietic Compartment:
- Stromal Cell (hematopoietic inductive microenvironment)
- Venous Sinusoids
(pic)
Structure of Bone Marrow: Endothelial Cell
Form a continour layer of interconnected cells lining the blood vessels. A basal lamina seperates endothelial cells from the branching stromal cell (PIC)