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Histology > Biliary Tract > Flashcards

Biliary Tract Flashcards

1
Q

Bile Flow

A

Hepatocyte->Duodenum

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2
Q

Biliary Tract 2 portions:

A

intrahepatic portion and extrahepatic portion

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3
Q

Hering’s Canals are lined by…

A

Cuboidal Cholangiocytes

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4
Q

What are Hering’s Canals?

A

The initial ductules that receive bile from the canaliculi AKA Bile Ducts

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5
Q

Cholangiocytes line…

A

the hepatic, systic, and common bile ducts

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6
Q

The hormone secretin stimulates cholangiocytes to…

A

secrete water and bicarbonate (alkalize) into bile to continue movement in ducts

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7
Q

What happens when the hepatopancreatic sphincter (of Oddi) is closed?

A

Bile must flow up the cystic duct into the gall bladder and accumilate

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8
Q

Function of Gallbladder

A

Stores, concentrates, and releases bile, NO bile synthesis.

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9
Q

What does bile promote?

A

Bile promotes re absorption of fat and carries bilirubin to the duodenum

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10
Q

What characterizes the lumen of the gall bladder?

A

Mucosal folds

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11
Q

Gall Bladder is lined by…

A

Simple Columnar Cells, Lamina Propria, Muscularis, External Adventia

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12
Q

Exocrine Gallbladder EXOCRINE Function

A

Produces bile (82% water, bile acids, bilirubin, electrolytes)

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13
Q

Bile is for…

A
  1. emulsifying (solublising) fats
  2. waste excretion (bilirubin from Hb breakdown; cholesterol; metabolites)
    90% bile is reclaimed-10% synthesized de novo
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14
Q

What is the purpose of the Spiral Fold?

A

It keeps the cystic duct open at all times! (because of spiral structure)

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15
Q

Cholecystokinin (CCK) function

A
  • Causes the smooth muscle cells in the gall bladder to contract
  • causes the hepatopancreatic aphincter (of oddi) to relax allowing bile to enter the duodenum
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16
Q

Enterohepatic Pathway

A

Once continued along the Duodenum, About 90% of bile acids are reabsorbed (especially in the ileum) and returned to the liver via the portal venous system (PIC)

17
Q

The narrowest part of the extrahepatic bilary tract is at the…

A

major duodenum papilla (sphincter of oddi)

18
Q

Sphincter of Oddi

A

Acts like a valve recieving from the Bile Duct and Pancreatic Duct and goes into the Duodenum

19
Q

What gives Feces its brown color?

A

Bilirubin- which is moving the Metabolic Product of RBC (Heme Component) into the small intestine some of which is metabolized and the rest is excreted

20
Q

What facilitates the expulsion of bile from the glalbladder?

A

Smooth muscle contraction

Histology (23 decks)

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