Biliary Tract

Question 1

Bile Flow

Answer 1

Hepatocyte->Duodenum

Question 2

Biliary Tract 2 portions:

Answer 2

intrahepatic portion and extrahepatic portion

Question 3

Hering’s Canals are lined by…

Answer 3

Cuboidal Cholangiocytes

Question 4

What are Hering’s Canals?

Answer 4

The initial ductules that receive bile from the canaliculi AKA Bile Ducts

Question 5

Cholangiocytes line…

Answer 5

the hepatic, systic, and common bile ducts

Question 6

The hormone secretin stimulates cholangiocytes to…

Answer 6

secrete water and bicarbonate (alkalize) into bile to continue movement in ducts

Question 7

What happens when the hepatopancreatic sphincter (of Oddi) is closed?

Answer 7

Bile must flow up the cystic duct into the gall bladder and accumilate

Question 8

Function of Gallbladder

Answer 8

Stores, concentrates, and releases bile, NO bile synthesis.

Question 9

What does bile promote?

Answer 9

Bile promotes re absorption of fat and carries bilirubin to the duodenum

Question 10

What characterizes the lumen of the gall bladder?

Answer 10

Mucosal folds

Question 11

Gall Bladder is lined by…

Answer 11

Simple Columnar Cells, Lamina Propria, Muscularis, External Adventia

Question 12

Exocrine Gallbladder EXOCRINE Function

Answer 12

Produces bile (82% water, bile acids, bilirubin, electrolytes)

Question 13

Bile is for…

Answer 13

1. emulsifying (solublising) fats
2. waste excretion (bilirubin from Hb breakdown; cholesterol; metabolites)
   90% bile is reclaimed-10% synthesized de novo

Question 14

What is the purpose of the Spiral Fold?

Answer 14

It keeps the cystic duct open at all times! (because of spiral structure)

Question 15

Cholecystokinin (CCK) function

Answer 15

• Causes the smooth muscle cells in the gall bladder to contract
• causes the hepatopancreatic aphincter (of oddi) to relax allowing bile to enter the duodenum

Question 16

Enterohepatic Pathway

Answer 16

Once continued along the Duodenum, About 90% of bile acids are reabsorbed (especially in the ileum) and returned to the liver via the portal venous system (PIC)

Question 17

The narrowest part of the extrahepatic bilary tract is at the…

Answer 17

major duodenum papilla (sphincter of oddi)

Question 18

Sphincter of Oddi

Answer 18

Acts like a valve recieving from the Bile Duct and Pancreatic Duct and goes into the Duodenum

Question 19

What gives Feces its brown color?

Answer 19

Bilirubin- which is moving the Metabolic Product of RBC (Heme Component) into the small intestine some of which is metabolized and the rest is excreted

Question 20

What facilitates the expulsion of bile from the glalbladder?

Answer 20

Smooth muscle contraction