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PHYSIOLOGY > HEMATOPOEISIS > Flashcards

HEMATOPOEISIS Flashcards

1
Q

Blood is 45% cells, also know as pecent packed cell volume

____________ indicator of anemia, polycythemia and other conditions

A

hematocrit

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2
Q

60%
transports lipids, steroid hormones

A

albumin

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3
Q

transport ions, many different proteins with a variety of functions
has a globulin classes alpha, beta and gamma
35%

A

globulins

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4
Q

granular leukocytes (granulocytes)

A

neutrophils eosinophils basophils

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5
Q

agranular leukocytes (agrunolocytes)

A

lymphocytes monocytes

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6
Q

in early week of embryo period ____ is the site of hemopoiesis

A

yolk sac

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7
Q

location of blood cell formation is the second trimester of pregnancy

A

liver spleen lymph node

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8
Q

3rd trimester location of blood cell formation

A

bone marrow

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9
Q

develops into RBS

A

proerythroblasts

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10
Q

develop into basophils, neutrophils, and eosinophils

A

myeloblasts

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11
Q

develop into lymphocytes

A

lymphoblasts

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12
Q

develop into monocytes

A

monoblasts

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13
Q

develop into platelets

A

megakaryoblasts

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14
Q

all blood cells are formed from _______ to committed cells

A

pluripotential hematopoietic stem cells

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15
Q

promotes the growth and reproduction of all the different types of stem cells whereas others induce growth of a specific type of committed stem cells

A

interleukin 3

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16
Q

committed stem cells lose their capacity for self-renewal, they become irreversibly committed

A

progenitor cells

17
Q

plasma membrane contain _____ an elastic spectrin an elastic protein give erythrocytes their flexibility or bag-like

A

spectrin

18
Q

indication of mean corpuscular hemoglobin (MCH)

ex. hyper/hypochromic, normochromic

A

chromasia

19
Q

cells of abnormal size; indication of mean corpuscle volume (MCV)

example is micro/macrocytic, normocytic

A

anisocytosis

20
Q

cells of abnormal shape in red blood cells
sickle cell, spherocytosis

A

poikilocytosis

21
Q

_____________ causes RBC to cluster and increases their effective density

A

fibrinogen

22
Q

made up of two alpha and two beta chains a protein

A

globin

23
Q

iron containing pigemnt part which binds with oxygen

A

heme group

24
Q

most common in an adult human hemoglobin which is the combination of 2 alpha and 2 beta chains

A

hemoglobin A

25
Q

hemoglobin bound to oxygen, oxygen loading takes place in the lungs

A

oxyhemoglobin

26
Q

hemoglobin after oxygen diffuses into tissues (reduced Hb)

A

deoxyhemoglobIn

27
Q

hemoglobin bound to carbon dioxide, carbon dioxide loading takes place in tissues

A

carbaminohemoglobin

28
Q

valine is substituted for glutamic acid when exposed to low oxygen tension

A

sickle cell anemia

29
Q

due to congenital absence of dihydronicotinamide adenine dinulceotide (NADH) methemoglobin reductase system that converts methemoglobin back to hemoglobin

A

hereditary methemoglobinemia

30
Q

formed if blood is exposed to certain drug or oxidizing agent which converts ferrous to ferric ion

A

methemoglobin

31
Q

iron that binds to protein

A

apotransferrin

32
Q

iron travels in circulation

A

transferrin

33
Q

extremely insoluble; toxic to cells; iron overload

A

hemosiderin

34
Q

final stage before mature RBC, released into blood where final maturation occurs

A

reticulocyte

35
Q

stimulates RBC production
formed in response to hypoxia

A

erythropoietin

36
Q

in people living in high altitude where atmospheric oxygen is low

A

polycythemia

37
Q

due to genetic abberation in the hemotocytoblastic cells that produce blood cells

increase in total blood volume
increase viscosity of blood

A

polycythemia vera

PHYSIOLOGY (33 decks)

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