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Block 5 > Head and Neck 2 > Flashcards

Head and Neck 2 Flashcards

1
Q

singer’s nodules

A

bilateral

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2
Q

vocal cord polyps

A

unilateral

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3
Q

reactive nodules

A

singer’s nodules
polyps
smoker or singer

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4
Q

description of nodules

A

smooth, rounded
sessile or pedunculate
myxoid CT covered by squamous epithelium

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5
Q

squamous papilloma

A

benign neoplasm
soft, rasberry like
fingerlike projections
can occlude trachea

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6
Q

virus associated with squamous papillomas

A

HPV6, 11

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7
Q

risk factors for laryngeal carcinoma

A

cigarette smoking

alcohol

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8
Q

description of laryngeal cancer

A

ulcerating, fungating lesions

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9
Q

symptoms of laryngeal cancer

A

persistent hoarseness
dysphagia
dysphonia

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10
Q

branchial cysts

A

remnants of branchial arches or salivary inclusions in cervical nodes
circumscribed
lymphoid tissue inside
clear watery/mucinous with cellular debris
lateral

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11
Q

thyroglossal cyst

A

remnants of thyroid tract
lymphoid aggregates in walls
recur if not fully excised
medial

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12
Q

paragangliomas

A

neuroendocrine cell clusters associated with ANS

recur with incomplete resection

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13
Q

mutation associated with paragangliomas

A

MENII

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14
Q

mucocele

A

post traumatic blockage/rupture of salivary gland duct

swollen, blue

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15
Q

treatment of mucocele

A

excision

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16
Q

most common salivary gland lesion

A

mucocele

17
Q

most common benign salivary gland tumor

A

pleomorphic adenoma

18
Q

mutation in pleomorphic adenoma

A

PLAG1

19
Q

pleomorphic adenoma

A

mesenchymal and epithelial cell components
painless, slow growing
low recurrence after excision
risk of malignant transformation increases overtime

20
Q

carcinoma ex pleomorphic adenoma

A

epitheilal malignancy from pleomorphic adenoma

21
Q

sarcoma

A

mesenchymal malignancy from pleomorphic adenoma

22
Q

true malignant mixed tumor

A

epithelial and mesenchymal malignancy from pleomorphic adenoma

23
Q

second most common benign salivary gland tumor

A

warthin tumor

24
Q

warthin tumor

A

papillary structure with oncolytic cells surrounding lymphoid material
usually parotid gland

25
Q

mutation associated with mucoepidermoid carcinoma

A

METC1-MAML2

26
Q

most common malignant tumor of salivary glands

A

mucoepidermoid carcinoma

27
Q

mucoepidermoid carcinoma

A

mixture of squamous, mucus secreting, intermediate cells

usually in parotid

28
Q

adenoid cystic carcinoma

A 
slow growing, recurrent
perineural invasion- grows up nerves
common dissemination
aggressive treatment required
cribriform pattern histologically
29
Q

actinic cell carcinoma

A

looks like normal serous acing cells
usually in parotid
can metastasize to lymph nodes
good 5 year survival

Block 5 (27 decks)

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