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VMS 1006 > Haematopoietic system and component parts; part 1 > Flashcards

Haematopoietic system and component parts; part 1 Flashcards

1
Q

Where do blood cells arise from?

A

The bone marrow

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2
Q

What is Erythropoiesis?

A

Production of Red Blood Cells

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3
Q

What is a reticulocyte?

A

The final cell type of an erythrocyte before maturation

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4
Q

What is the function of platelets?

A

They mediate blood coagulation

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5
Q

What is the function of leukocytes?

A

They remove bacteria and cell debris by the process of phagocytosis and promote the process of wound healing

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6
Q

What are the homeostatic functions of phagocytic leukocytes?

A

Tissue remodelling and removal of dead cells

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7
Q

What do platelets attract via cell signalling?

A

Leukocytes and WBC’S to promote wound healing

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8
Q

What is the main function of Neutrophils?

A

Phagocytic, they kill bacteria and fungi by microbicidial mechanisms

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9
Q

What are the functions of macrophages?

A

Phagocytosis and tissue repair?

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10
Q

What do monocytes develop into?

A

Monocytes are found in the blood stream and then develop into macrophages in the tissue

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11
Q

What are platelets mainly responsible for?

A

primary homeostasis, (plugging damaged blood vessels)

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12
Q

How do Eosinophils stain?

A

Very strongly pink, contain very prominent granules

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13
Q

What is the main function of Eosinophils?

A

Provide immunity against helminth infections and contribute towards allergic reactions

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14
Q

How do basophils stain?

A

Dark blue stain

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15
Q

What is the function of basophils?

A

they participate in inflammatory reactions, e.g releasing histamine

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16
Q

What is the main function of monocytes?

A

rapidly respond to inflammatory stimuli and migrate in large numbers to infected/ injured tissues

17
Q

What do mast cells pass through the blood as?

A

immature cells, they then mature when they migrate into the tissues

18
Q

What are lymphoid cells?

A

a type of WBC with a large, deeply staining nucleus- found in the lymph system

19
Q

What immune system are lymphoid cells a part of?

A

the adaptive immune system

20
Q

What are the two cell types lymphocytes are most broadly categorised into?

A

Helper and Cytoxic cells

21
Q

What is the function of helper T-Cells?

A

drive immune responses against different types of pathogen

22
Q

What is the function of Cytoxic T-Cells?

A

Recognise and kill infected cells

23
Q

What do plasma cells secrete upon activation?

A

immunoglobin (antibodies that can mediate a broad range of effects upon pathogens)

24
Q

What other cells can B-Cells act as?

A

Antigen Presenting Cells

25
Q

What are myeloid cells?

A

any cell that derives from the bone marrow

26
Q

Why are platelets mainly found in mammals?

A

They evolved to stop haemorrhage during childbirth

VMS 1006 (31 decks)

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