GI Cancer Drugs

Question 1

Anal Cancer Regimen?

Answer 1

Radiation + Cisplatin, 5-FU, and Mitomycin

Question 2

CRC regimen

Answer 2

FOLOX (5-FU+Leucovorin+Oxaliplatin)

Question 3

What is the alternate CRC regimen

Answer 3

FOLFIRI (5-FU + Leucovorin + Irinotecan)

Question 4

What can 5-FU be replaced with?

Answer 4

Capecitabine

Question 5

What drugs can be used in pts without KRAS mutations?

Answer 5

Bevacizumab and Cetuximab

Question 6

Esophageal Cancer Treatment Regimen

Answer 6

Cisplatin + 5-FU + Vinblastine

Question 7

Gastric cancer pts should all be screened for?

Answer 7

Her2

Question 8

What is the treatment regimen for gastric cancer pts with Her2 mutations?

Answer 8

5-FU + Cisplatin + Traztuzumab

Question 9

GI Carcinoid tumor tx?

Answer 9

Octreotide—decreases hormone production, 12 mos regimen

Question 10

Finish Regimens

Answer 10

ok

Question 11

Bevacizumab mech

Answer 11

VEGF mAb

Question 12

Bevacizumab AE

Answer 12

Gi perf, wound dehiscence, HTN

Question 13

Cetuximab mech

Answer 13

EGFR mAb

Question 14

Cetuximab AE

Answer 14

Cardiac/ Respiratory arrest, sudden death

Question 15

Trastuzumab mech

Answer 15

HER-2 mAb

Question 16

Erlotinib mech

Answer 16

EGFR- RTKI

Question 17

Erlotnib AE

Answer 17

bleeding, eye toxicity and interstitial lung dz

Question 18

Cisplatin does what

Answer 18

DNA intra-strand crosslinks