Gen. Bio. PPTs: The Cell Cycle Flashcards
The actual division of the cell into two new cells.
Cytokinesis
The division of the nucleus of the cell into two new nuclei.
Karyokinesis
Sometimes cells go through _____ without going through _______.
mitosis; cytokinesis
Anatomy Chromosome.
What are the 5 main parts?
p-arm, q-arm, centromere, telomere, chromatids
Anatomy Chromosome.
Point where sister chromatids are joined together.
Centromere
Anatomy Chromosome.
SHORT arm; upward
p-arm
Anatomy Chromosome.
LONG arm; downward
q-arm
Anatomy Chromosome.
Tips of the chromosome.
Telomere
Fibrous form of DNA and protein.
Chromatin
IDENTICAL structures that result from chromosome replication, formed during S phase.
Sister Chromatids
A sequence of phase in the life cycle of the cell. Period between two sequential divisions.
Cell Cycle
Two main phases in the cell cycle:
Interphase & Mitotic Phase
What are the three subparts of Interphase?
Growth (G1)
Synthesis (S)
Growth (G2)
Interphase. The cell just finished dividing so it is recovering from mitosis.
G1 or Gap 1
Interphase. Here, the DNA replicates.
S or Synthesis stage
Interphase. This is preparation for mitosis. Organelles are replicated. More growth occurs.
G2 or Gap 2
These are the cell’s control system. A cell cycle stops until a go-ahead signal is received here.
Checkpoints
What are the 3 checkpoints in the cell cycle?
G1 checkpoint, G2 checkpoint, M checkpoint
Which of the 3 checkpoints is the most critical?
G1 checkpoint: It is the first protection from damaged DNA. If there is no go-ahead signal, the cell exits and enters G0, a nondividing state. While if it does, the cell continues on the cycle.
Usually, if the cell pass this stage, it will complete the S, G2, and M phases and divide.
When does mitosis begin?
After Gap 2 and ends before Gap 1
Two types of regulatory proteins involved in cell cycle control:
Cyclins & Cyclin-dependent Kinases (Cdks)
Cdks activity (a) ________ during the cell cycle because it is controlled by (b) _________, so named because their concentrations (c) ________ with the cell cycle.
a. fluctuates
b. cyclins
c. vary
A cyclin-Cdk complex that triggers a cell’s passage past the G2 checkpoint into the M phase.
MPF (maturation-promoting factor)