FOM 5.1.3 Flashcards

1
Q

What are each of these?

A
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2
Q

What are the major characteristics of this cell?

A
  • granules contain major basic protein and other proteins that kill parasites
  • contain histaminase that limits the inflammatory process
  • can phagocytose antigen-antibody complexes
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3
Q

What are the characteristics of this cell?

A
  • band neutrophil
  • immature neutrophil
  • aka stab cell
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4
Q

What are the characteristics of these?

A
  • Maintain hemostasis
  • Serotonin
  • ADP
  • Thromboxane A2
  • Adhere to endothelium promote vessel repair, blood clotting and vasoconstriction
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5
Q

What is this cell and what are the identifying characteristics?

A

Basophil - large dense granules

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6
Q

What are each of these cells?

A

Top left- neutrophil

Top right - monocyte

Bottom left - monocyte

Bottom right - basophil and platelets

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7
Q

What are the characteristics of this cell?

A

Neutrophil

Migrate to sites of infection and phagocytose bacteria

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8
Q

What are the characteristics of this cell?

A

Monocyte - will become tissue macrophage

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9
Q

What is the role of a basophil?

A

Plays a role in hypersensitivity reaction

Secretes histamine

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10
Q

What is this cell and what are the defining characteristics?

A

Neutrophil - multilobed nucleus and relatively small abundant granules

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11
Q

What are each of these cell types?

A

Top Left picture - left lymphocyte ; right monocyte

Top right - Monocytes

Bottom left - eosinophil

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12
Q

What will lymphocytes further differentiate into?

A

T-cells and B-cells

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13
Q

What are each of these cells?

A

Top left - basophil

Top right - eosinophil

Bottom right - neutrophil

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14
Q

What are each of the cells in this image?

A

Top left picture - left neutrophil, middle monocyte, right basophil

Right - neutrophil

Bottom left - monocyte

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15
Q

What are each of these?

A

Top left - basophil

Top right - band cell and mature segmented neutrophils

Bottom left- eosinophil

Bottom right - erythrocyte

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16
Q

What is this and what are the defining characteristics?

A

Eosinophil - electron dense and electron lucent regions within the same granule

17
Q

What are each of these cells?

A

Top left - lymphocyte

Right - basophil

Bottom left - left - lymphocyte right - eosinophil

18
Q

What are each of these?

A

Left - basophil

Right - lymphocyte

19
Q

What are each of these?

A
20
Q

What are each of these?

A

Top neutrophil

Bottom - monocyte

21
Q

What is this?

A

Sickle cell anemia

22
Q

What is this?

A

Microcytic anemia - note small erythrocytes

23
Q

What is this?

A

Macrocytic anemia - note the very large erythrocytes

24
Q

What is this large cell taken from the bone marrow and what does it produce?

A

Megakaryocyte - produces platelets it will remain in the bone marrow compartment and shed platelets into the vascular space

25
Q

These are?

A

Plasma cells

26
Q

What is the composition of whole blood?

A

55% plasma and 45% erthrocytes and the buffy coat with platelets and leukocytes

27
Q

What is the difference between serum and plasma?

A

Serum contains an anticoagulant so there is no fibrinogen

28
Q

What are the two types of bone marrow and what are their differences?

A

Yellow - not producing blood cells

Red - actively producing blood cells

29
Q

What is the controlling mechanism of erythropoiesis?

A

Oxygen tension is sensed in the kidney. Release of EPO which leads to increased proliferation, decreased apoptosis, increased hemoglobin production, increased reticulocyte release

30
Q

What is mean corpuscular volume?

A

Size of the RBC

31
Q

What is MCHC?

A

Mean corpuscular hemoglobin concentration - Hb concentration per cell

32
Q

What is MCH?

A

Mean corpuscular hemoglobin - weight of Hb per cells

33
Q

What is RDW?

A

Red cell distribution width - variation in size

34
Q

What are some of the effects of abnormally high glycation on erythrocyte function?

A

Increased adhesion to endothelium

Decreased membrane fluidity

Decreased BPG activity