FOM 5.1.3 Flashcards

1
Q

What are each of these?

A
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2
Q

What are the major characteristics of this cell?

A
  • granules contain major basic protein and other proteins that kill parasites
  • contain histaminase that limits the inflammatory process
  • can phagocytose antigen-antibody complexes
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3
Q

What are the characteristics of this cell?

A
  • band neutrophil
  • immature neutrophil
  • aka stab cell
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4
Q

What are the characteristics of these?

A
  • Maintain hemostasis
  • Serotonin
  • ADP
  • Thromboxane A2
  • Adhere to endothelium promote vessel repair, blood clotting and vasoconstriction
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5
Q

What is this cell and what are the identifying characteristics?

A

Basophil - large dense granules

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6
Q

What are each of these cells?

A

Top left- neutrophil

Top right - monocyte

Bottom left - monocyte

Bottom right - basophil and platelets

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7
Q

What are the characteristics of this cell?

A

Neutrophil

Migrate to sites of infection and phagocytose bacteria

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8
Q

What are the characteristics of this cell?

A

Monocyte - will become tissue macrophage

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9
Q

What is the role of a basophil?

A

Plays a role in hypersensitivity reaction

Secretes histamine

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10
Q

What is this cell and what are the defining characteristics?

A

Neutrophil - multilobed nucleus and relatively small abundant granules

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11
Q

What are each of these cell types?

A

Top Left picture - left lymphocyte ; right monocyte

Top right - Monocytes

Bottom left - eosinophil

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12
Q

What will lymphocytes further differentiate into?

A

T-cells and B-cells

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13
Q

What are each of these cells?

A

Top left - basophil

Top right - eosinophil

Bottom right - neutrophil

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14
Q

What are each of the cells in this image?

A

Top left picture - left neutrophil, middle monocyte, right basophil

Right - neutrophil

Bottom left - monocyte

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15
Q

What are each of these?

A

Top left - basophil

Top right - band cell and mature segmented neutrophils

Bottom left- eosinophil

Bottom right - erythrocyte

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16
Q

What is this and what are the defining characteristics?

A

Eosinophil - electron dense and electron lucent regions within the same granule

17
Q

What are each of these cells?

A

Top left - lymphocyte

Right - basophil

Bottom left - left - lymphocyte right - eosinophil

18
Q

What are each of these?

A

Left - basophil

Right - lymphocyte

19
Q

What are each of these?

20
Q

What are each of these?

A

Top neutrophil

Bottom - monocyte

21
Q

What is this?

A

Sickle cell anemia

22
Q

What is this?

A

Microcytic anemia - note small erythrocytes

23
Q

What is this?

A

Macrocytic anemia - note the very large erythrocytes

24
Q

What is this large cell taken from the bone marrow and what does it produce?

A

Megakaryocyte - produces platelets it will remain in the bone marrow compartment and shed platelets into the vascular space

25
These are?
Plasma cells
26
What is the composition of whole blood?
55% plasma and 45% erthrocytes and the buffy coat with platelets and leukocytes
27
What is the difference between serum and plasma?
Serum contains an anticoagulant so there is no fibrinogen
28
What are the two types of bone marrow and what are their differences?
Yellow - not producing blood cells Red - actively producing blood cells
29
What is the controlling mechanism of erythropoiesis?
Oxygen tension is sensed in the kidney. Release of EPO which leads to increased proliferation, decreased apoptosis, increased hemoglobin production, increased reticulocyte release
30
What is mean corpuscular volume?
Size of the RBC
31
What is MCHC?
Mean corpuscular hemoglobin concentration - Hb concentration per cell
32
What is MCH?
Mean corpuscular hemoglobin - weight of Hb per cells
33
What is RDW?
Red cell distribution width - variation in size
34
What are some of the effects of abnormally high glycation on erythrocyte function?
Increased adhesion to endothelium Decreased membrane fluidity Decreased BPG activity