Exam 3: Cardiovascular System Flashcards
What is the function of veins?
collect blood from microvasculature and bring to heart
What are the 3 tunics of all vessels?
Tunica intima
Tunica media
Tunica adventitia
Parts of Tunica Intima
Endothelium
Subendothelial Layer
Internal Elastic Membrane/Lamina
What orientation is the Tunica Intima seen in?
longitudinal orientation
What makes up the subendothelial layer of the tunica intima?
Fine collagen fibers + elastic (sometimes)
What is characteristic about the internal elastic lamina of the tunica intima?
thick, elastic present
“sheet” NOT fiber
holes for diffusion
What orientation is the Tunica Media?
Circular orientation
What are the two components of Tunica Media?
Smooth muscle
Connective tissue
What is the function of the Tunica Media?
constricting to facilitate blood flow
What orientation is the Tunica Adventitia?
longitudinal orientation
What two structures are seen in the Tunica Adventitia?
Vasa vasorum
Nervi vasorum
What makes up the Tunica Advenitita?
collagen and/or elastic fibers
Vasa vasorum
little vessels that branch and go into adventitia & media
ONLY sympathetic innvervation
Nervi vasorum
nerves within vasa vasorum
seen in larger vessels
What are examples of Elastic Aa?
Aorta
Brachiocephalic Trunk
What layer is the thickest in Elastic Aa and what makes it characteristic?
Tunica media
alternating smooth muscle & elastic layers
What part of the Tunica Intima is thick in Elastic Aa?
subendothelial layer
What part of the Tunica Intima is thin in the Elastic Aa?
Internal Elastic Lamina
What structures are easiest to see in the Elastic Aa?
Vasa vasorum & Nervi vasorum
What are examples of Muscular Aa?
renal A
brachial A
femoral Aa
What part of the Tunica Intima is thick in Muscular Aa?
Internal Elastic Lamina
Muscular Aa have the thickest of the all the vessels in which layer?
Tunica Media
What is characteristic of the Tunica Media of Muscular Aa?
smooth muscle dominates
less elastic lamina
What is different about the Tunica Adventitia in Muscular vs. Elastic Aa?
More elastic fibers in MUSCULAR than ELASTIC Aa
What tunic is seen in arterioles and what is it characterized by?
Tunica Media
1-3 layers of smooth muscle
Meta-arteriole
arterioles right before capillaries
What tunic and what is it characterized by in Meta-arterioles?
Tunica Media
incomplete smooth muscle layer
Arteriovenous Anastomoses
direct connection from arteriole to venule (bypasses capillary bed when open)
Where are arteriovenous anastomoses located?
Skin & Intestines
bypassed in fight or flight
Capillary Tunics Characterization
ONLY endothelium layer
NO smooth muscle
NO adventitia
Pericytes
supportive, undifferentiated mesenchymal cells that change based on need
Where are pericytes located?
endothelial cell basal lamina
List Capillary Types
Continuous
Fenestrated
Porous
Sinusoid
Continuous Capillaries
NOT leaky, tight junctions
Location of Continuous Capillaries
muscle & nervous tissue
muscle- some exchange
nervous- NO exchange
Fenestrated Capillaries
Leaky | continuous basement membrane
Have fenestra
Selective exchange
Fenestra
openings by thin lipid monolayer in capillaries
Porous Capillaries
big openings | thick basement membrane
Porous Capillary Function
high pressure for filtration
Location of Porous Capillaries
Kidney
Sinusoid Capillaries
VERY leaky | endothelial cell gaps
Sinusoid Capillary Location
Liver
Bone Marrow
Endocrine System
Venules
right after capillaries
similar structure
What is unique about venules structure?
ONLY endothelium layer
Pericytes present
Which tunic is characteristic in Muscular Venules?
Tunica media
Develop layer of smooth muscle
Tunica Intima of Muscular Veins
have valves (folds of intima)
Dilation after valve from pressure
Function of Valves in Veins
unidirectional flow
prevent backflow
Tunica Media of Muscular Veins
3-4 layers smooth muscle
small CT layer
Tunica Adventitia of Muscular Veins
blend with surrounding CT
What are examples of large veins?
cranial & caudal vena cava
What is unique about the Tunica Intima in Large Veins?
Thin internal elastic lamina
What is unique about the Tunica Media of Large Veins?
VERY thin
discontinuous smooth muscle layer
collagen fibers
What is unique about the Tunica Adventitia of Large Veins?
thick bundles of smooth muscle
Function: “stiffen” vessel
What orientation are the smooth muscle bundles in the Tunica Adventitia of Large Veins?
longitudinal
Carotid Sinus
baroreceptors
cells in wall in beginning of internal carotid A
What is the function of the Carotid Sinus?
sense pressure & release chemicals to influence blood pressure
Carotid Body
group of chemoreceptors outside vessel
What is the function of the carotid body?
regulate blood volume
What are the 3 tunics of the heart?
Endocardium
Myocardium
Epicardium
What are the layers of the Endocardium of the Heart?
Endothelium
Subendothelial Layer
Subendocardial Layer
What makes up the subendothelial layer of the endocardium?
Collagen + elastic fibers
Where are Purkinje Fibers located?
Subendocardial Layer of Endocardium
What is the function of Purkinje Fibers?
Conduct heart impulse
Which part of the tunica intima of vessels is not located in the endocardium?
Internal Elastic Lamina
Cardiac Valves
specialized folds of endocardium
covered by endothelium
middle = thickening of subendothelial layer
What two structures are not located in cardiac valves?
Purkinje cells
Subendocardial layer
Where do atrial myocytes secrete ANP?
Myocardium
What orientation is cardiac muscle in the myocardium?
Spirally oriented
What secretes ANP?
atrial myocytes in the myocardium
What is ANP’s function?
influence sodium absorption in the kidney
A thick layer of ____ covers the heart (in epicardium)
Collagen
What is the collagen in the epicardium continuous with?
the tunica adventitia of vessels coming in and out
Fibrous pericardium
thickening of adventitia in epicardium
What are the two layers of the epicardium?
Visceral Layer of Serous Pericardium
Serous Membrane
Which layer of the epicardium is within the fibrous pericardium?
Visceral Layer of Serous Pericardium
Which layer of the epicardium is directly applied to the heart?
Serous Membrane
What are the 3 structures apart of the impulse conducting system of the heart?
Sinoatrial Node
Atrioventricular Node
Bundle of His (atrioventricular bundle)
What is the order of impulse conduction in the heart?
SA node –> AV node –> Bundle of His
Which part of the impulse conducting system of the heart has purkinje cells?
Bundle of His (atrioventricular bundle)
What is the cardiac skeleton?
connective tissue of the heart
Annuli Fibrosi
“Fibrous ring” in the heart
What is the function of the Annuli Fibrosi?
to give heart valves rigidity
Trigona Fibrosa
cartilage or bone (ruminants) in CT around valves of heart
What is the function of the Trigona Fibrosa in the heart?
Support valves