Exam 2: Blood & Bone Marrow Flashcards
Central Pallor
light central region of RBC (biconcave)
Howell-Jolly Bodies
retained chromatin in RBC
small dot
Rouleau Formation
stacks of RBC
artifact of prep
What species is most common for rouleau formation?
horse blood
Anisocytosis
difference in size of RBC
What species is most common with anisocytosis?
cattle blood
Poikilocytosis
difference in shape of RBC
What species is most common for poikilocytosis?
goat blood
Crenation
spikes on RBC
artifact of prep
What species is most common for crenation in RBC?
cat blood
Heinz bodies
denatured hemoglobin in RBC
white dots at periphery
What species is most common for Heinz bodies?
normal to see a few in cat blood
Leukocyte (+types)
WBC
granulocytes
agranulocytes
Specific granules
secondary granules only present in granulocytes
Azurophilic granules
primary granules / non-specific
present in all leukocytes
Neutrophil
granulocyte | neutral stain
most common leukocyte other than ruminants
F: break down bacteria/debris
granules have lactoferrin
Basophil
granulocyte
very few present
F: allergic reaction, heparin/histamine in granules
Eosinophil
granulocyte
F: kill parasite / antigen-antibody complex
attracted to histamine (have histaminase to break down)
Agranulocyte
leukocyte w/o specific granules, but has azurophilic granules
Lymphocyte
agranulocyte
most common WBC in ruminants
function: immune response
Monocyte
agranulocyte
form osteoclasts
become macrophages