Ethanol Metabolism Flashcards

1
Q

The conversion of ethanol to acetaldehyde happens in the _____.

A

cytosol

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2
Q

The conversion of acetaldehyde to acetate happens in the ______.

A

mitochondria

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3
Q

Ethanol to acetaldehyde: alcohol dehydrogenase :: acetaldehyde to acetate: ______

A

acetaldehyde dehydrogenase

It operates in a zero order kinetics

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4
Q

This drug blocks acetaldehyde dehydrogenase thereby increasing acetaldehyde level increasing hangover symptoms.

A

Disulfram

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5
Q

This drug block alcohol dehydrogenase. This drug is used as an antidote for methanol and ethylene glycol overdose.

A

Fomepizole

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6
Q

This is the limiting agent in ethanol metabolism.

A

NAD+

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