Complex Molecules

Question 1

Oligosacharides attach to this AA and O-linked to make glycoprotein

Answer 1

Serine

Mnemonic = OG SER

Question 2

Oligosachides attached to serine to form glycoprotein is synthesized in the ___

Answer 2

golgi bodies

Question 3

Oligosaccharides attached to this AA is N-linked (to make glycoprotein)

Answer 3

Asparagine

Question 4

Oligosaccharide attached to asparagine to make glycoprotein is synthesized in the

Answer 4

Endoplasmic reticulum

Question 5

Cell surface antigenicity is due to what complex molecule?

Answer 5

Glycoprotein

Question 6

[Complex molecule]

Transport proteins with glycoprotein

Answer 6

Transferrin

Ceruloplasmin

Question 7

[Complex molecule]

Hormone that contains glycoprotein

Answer 7

HCG, TSH

Question 8

[Complex molecule]

lubricant protective int he GIT and urogenital tract that has glycoprotein

Answer 8

mucin

Question 9

[Complex molecule]

Glycosaminoglycans is mostly made of

Answer 9

CHO

Question 10

Glycosaminoglycas are unbranced polysaccharides consisting of alternating ___-

Answer 10

acidic sugar-aminosugar

Question 11

[Glycosaminoglycans]

What are examples of acid sugars

Answer 11

Glucuronic Acid

Iduronic acid

Question 12

[Glycosaminoglycans]

examples of amino sugar

Answer 12

Glucosamine

Galactosamine

Question 13

Which GAG is not linked to a proteoglycan core

Answer 13

hyaluronic acid

Question 14

[Glycosaminoglycans]

Needed for cell migration and wound repair

Answer 14

hyaluronic acid

Question 15

[Glycosaminoglycans]

seen in carilage

Answer 15

Chondroitin sulfate

most abundant

Question 16

[Glycosaminoglycans]

maintains corneal transparency

Answer 16

keratan sulfate

Question 17

[Glycosaminoglycans]

anticoagulat

Answer 17

heparin

Question 18

[Glycosaminoglycans]

receptor for cell growth and cell-cell communication

Answer 18

heparan sulfate

Question 19

[Glycosaminoglycans]

maintain GAG of skin

Answer 19

dermatan sulfate

Question 20

[Glycerophospholipids]

What bond maintains the binding of an R-OH to the diacylglycerol

Answer 20

Phosphodiester bind

Question 21

[Glycerophospholipids]

Most abundant glycerophospholipid

Answer 21

lecithin

Question 22

[Glycerophospholipids]

storage of choline component of acetylcholine

Answer 22

Phosphatidylcholine

Question 23

[Glycerophospholipids]

cephalin, cell membrane inner leaflet

Answer 23

phosphatidylethanolamine

Question 24

[Glycerophospholipids]

plays a role in apoptosis

Answer 24

Phosphatidylserine

Question 25

[Glycerophospholipids] reservoir of arachidonic acid in cell membrane

Answer 25

phosphatidylinositol

Question 26

[Glycerophospholipids] source of inositol triphosphate + DAG

Answer 26

phosphatidylinositol

Question 27

[Glycerophospholipids] lung surfactant

Answer 27

Dipalmitoyllecithin

Question 28

[Glycerophospholipids] cross reacts with antibodies to syphilis

Answer 28

Cardiolipin

Question 29

What is the backbone of sphingophospholipids?

Answer 29

Sphingosine

Question 30

What is the only significant sphingophospholipid in humans?

Answer 30

Sphingomyelin

Question 31

___ is a complex molecule that is a derivative of ceramide in which a long chain FA is attached to sphingosine backbone

Answer 31

Glycosphingolipids

Question 32

[Glycosphingolipids] if hyrdogen atom is ttached

Answer 32

Ceramide

Question 33

[Glycosphingolipids] if glucose or galactose is attached

Answer 33

Cerebroside

Question 34

[Glycosphingolipids] if a di-, tri-, or tetrasaccharide is attached

Answer 34

globoside

Question 35

[Glycosphingolipids] if N-acetylneuraminic acid is attached

Answer 35

ganglioside

Question 36

[Glycosphingolipids] if sulfated glucose is attached

Answer 36

sulfatide

Question 37

What contributes to the asymmetry of the cell membrane outer leaflet?

Answer 37

glycosphingolipids

Question 38

___ are derived from 20 carbon FA arachidonic acid, cleaved by phospholipase A2

Answer 38

Eicosanoid

Question 39

What enzyme produces prostaglandin and thromboxane?

Answer 39

Cyclooxygenase

Question 40

What enzyme produces leukotrienes?

Answer 40

lipooxygenase

Question 41

[Eicosanoids] protect gastric mucosa

Answer 41

prostaglandin

Question 42

[Eicosanoids] Promotes platelet adhesion and aggregation

Answer 42

Thromboxane

Question 43

[Eicosanoids] stimulate vasodilation, inhibits thrombosis

Answer 43

Prostacyclin

Question 44

[Eicosanoids] Keeps PDA patent, used for erectile dysfunction

Answer 44

Alprostadil (PGE1)

Question 45

[Eicosanoids] Results in vasodilation and relaxation of smooth muscle used to induce labor

Answer 45

Prostaglandin E2

Question 46

[Eicosanoids] results in vasoconstriction and contraction of muscle, stimulates uterine contraction

Answer 46

PGF2alpha

Question 47

[Eicosanoids] slow reacting substances, potent airway constrictors

Answer 47

LTC4 LTD4 LTE4