Equine Immunity (part 2) Flashcards
Function of antibodies
Binds to the surface of the invading organism
-inactivates or renders the microorganism susceptible to destruction by the immune system
How does Cell mediated Immunity protect the body (specific functions)
- Activates antigen-specific T-cells that destroy infected cells
- Activates macrophages that destroy intracellular pathogens
- Activates NK (natural killer) cells that release a protein that kills the target cells
Neutrophil function
- When a wound occurs, neutrophils migrate out of the blood to rush to the wound and phagocytize the bacteria
- makes the pus
Role of Monocytes
Turn into a macrophage
Eosinophil function
Attack internal parasites
Lymphocyte function
Play major role in defending the host form both tumors and virally infected cells
- Includes B and T cells
Macrophage function
Engulf and then digest cellular debris and microbes in the body tissues
Platelet function
- Blood clotting
- No role in immunity
Complete Blood Count function
- Determines the number and types of blood cells present
- Can provide information about the status of the patient’s immune system
The Complete Blood Count tests for :
-Red blood cells
-White blood cells
- Platelets
-Other components
( hemoglobin, hematocrit)
Leukocytosis
White blood cell count increased above the normal range
- sign of illness
Leukocytosis occurs in
- Viral, bacterial, fungal, or parasitic infection
- cancer
- hemorrhage
- exposure to certain medications or chemicals including steroids
Leukopenia
Decrease in the number of circulating white blood cells in the blood
- happens when white blood cells are “used up” during infection and lead to a higher risk for infection
