Epithelial Tissue Flashcards

1
Q

Where does the apical domain of an epithelial cell face?

A

exterior surface/lumen of an enclosed cavity or tube

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2
Q

What is endothelium? What is it made of?

A

lining of blood and lymphatic vessels

made of simple squamous epithelia

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3
Q

What are goblet cells?

A

mucus-secreting cell found lining intestines and respiratory tract; help protect and collect debris

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4
Q

Where are simple cuboidal cells found?

A

kidney tubules, glands and associated ducts, terminal bronchioles, covering ovary

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5
Q

What are occluding junctions?

A

junctions that encircle cells near most apical surface –> can create impermeability of a layer of cells

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6
Q

What are flagella? Where do you find them?

A

modified motile cilia

sperm tail

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7
Q

What are the 4 types of apical specializations?

A

cilia, flagella, microvilli, and stereocilia

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8
Q

What are gap junctions?

A

fluid-filled channels that connect cells and mediate communication

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9
Q

What are nodal cilia?

A

embryonic, have role in L/R axis determination

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10
Q

Where do you find keratinized stratified squamous cells?

A

epidermis of the skin

for barrier and protection

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11
Q

What are focal adhesions and hemidesmosomes made of?

A

integrins

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12
Q

What is the function of simple squamous epithelia?

A

exchange, barrier, and lubrication

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13
Q

What are motile cilia?

A

cilia that beat in a wave-like fashion to propel substances across tissue

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14
Q

What are stereovilli made of?

A

actin - provides rigidity

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15
Q

How do merocrine glands secrete?

A

secretion delivered in membrane-bound vesicles to apical surface –> exocytosis

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16
Q

What do mucous acini look like in stain?

A

very light, don’t take up dye

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17
Q

Where are urothelium cells found?

A

urinary blader, ureters, urethra

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18
Q

Where are pseudostratified columnar ciliate cells?

A

position of nuclei vary so it looks like multiple layers but is actually 1 layer
for absorption and secretion, debris and particulate movement

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19
Q

Where are simple squamous epithelial cells found? (5)

A

endothelium, mesothelium, lining alveoli in lungs, loop of henle in kidney, various ducts

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20
Q

What are hemidesmosomes?

A

intercellular junctions that anchor intermediate filaments to basement membrane

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21
Q

What are simple cuboidal cells? What is their function?

A

1 layer thick w/ round nuclei that make a tube

absorption, barrier, secretion

22
Q

What is mesothelium? What is it made of?

A

lining of serous membranes

made of simple squamous epithelia

23
Q

Where are nonkeratinized stratified squamous cells found?

A

oral cavity, portions of pharynx, esophagus, anus, vagina urethra, cornea
basically where there is friction and abrasion not on outermost skin

24
Q

Where are pseudostratified columnar ciliate cells found?

A

lining of nasal cavity, pharynx, trachea, bronchi

25
What are occluding junctions made of?
occludins, claudins
26
What are cilia made of?
microtubule based
27
What are stereovilli/stereocilia?
microvilli of unusual length - long and immotile
28
What are zonula adherens and what do they interact with?
type of anchoring junction | connect actin filaments cell to cell
29
What is a serous membrane?
epithelial tissue that lines specific internal cavities of body forms smooth 2 layered membrane lubricated by fluid derived from serum mesothelium is part of a serous membrane
30
Where are simple columnar cells found?
auditory tubes, uterus, oviducts, stomach, intestines, gallbladder
31
What is special about urothelium cells?
dome shaped cells at apical surface | stratified epithelium that allows for stretch and recoil of bladder
32
What is the function of simple columnar cells?
absorption and secretion
33
What does the lateral domain of an epithelial cell face?
adjacent cells
34
What are anchoring junctions made of?
cadherins
35
What are anchoring junctions?
lateral adhesions that link into cytoskeleton of adjacent cells zonula adherens macula adherens/desmosomes
36
How do apocrine glands secrete?
(mammary glands) release of apical portion of cell w/ cytoplasm in plasma membrane
37
Where do you mainly find cilia?
in the respiratory tract
38
What are primary cilia?
immotile cilia, function as chemosensors, osmosensors, mechanosensors
39
What do serous acini look like in stain?
very dark, take up dye heavily
40
What are gap junctions made of?
connexin
41
What type of epithelia is one layer thick?
simple epithelia
42
What is special about the apical layer of keratinized stratified squamous cells?
do not have nuclei
43
what is the basal domain of an epithelial cell to?
basal lamina; anchors cell to underlying connective tissue
44
Where are stereovilli/stereocilia restricted to?
epididymis and sensory cells of inner ear
45
What is the purpose of microvilli?
increase surface area of apical domain by 20-30x --> increase absorption
46
What are microvilli made of?
actin core
47
How do holocrine glands secrete?
secretion accumulates w/in cell --> apoptosis --> secretion and cell debris released
48
What are macula adherens/desmosomes and what do they interact with?
type of anchoring junction | connect intermediate filaments in adjacent cells
49
What are focal adhesions?
intercellular junctions that anchor actin filaments to basement membrane
50
What type of epithelia is more than one layer thick?
stratified epithelia
51
Where are stratified cuboidal cells found?
sweat glands and ducts, ovarian follicles, salivary gland ducts passageway function is important!