Epithelial Tissue Flashcards

1
Q

Where does the apical domain of an epithelial cell face?

A

exterior surface/lumen of an enclosed cavity or tube

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2
Q

What is endothelium? What is it made of?

A

lining of blood and lymphatic vessels

made of simple squamous epithelia

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3
Q

What are goblet cells?

A

mucus-secreting cell found lining intestines and respiratory tract; help protect and collect debris

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4
Q

Where are simple cuboidal cells found?

A

kidney tubules, glands and associated ducts, terminal bronchioles, covering ovary

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5
Q

What are occluding junctions?

A

junctions that encircle cells near most apical surface –> can create impermeability of a layer of cells

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6
Q

What are flagella? Where do you find them?

A

modified motile cilia

sperm tail

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7
Q

What are the 4 types of apical specializations?

A

cilia, flagella, microvilli, and stereocilia

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8
Q

What are gap junctions?

A

fluid-filled channels that connect cells and mediate communication

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9
Q

What are nodal cilia?

A

embryonic, have role in L/R axis determination

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10
Q

Where do you find keratinized stratified squamous cells?

A

epidermis of the skin

for barrier and protection

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11
Q

What are focal adhesions and hemidesmosomes made of?

A

integrins

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12
Q

What is the function of simple squamous epithelia?

A

exchange, barrier, and lubrication

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13
Q

What are motile cilia?

A

cilia that beat in a wave-like fashion to propel substances across tissue

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14
Q

What are stereovilli made of?

A

actin - provides rigidity

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15
Q

How do merocrine glands secrete?

A

secretion delivered in membrane-bound vesicles to apical surface –> exocytosis

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16
Q

What do mucous acini look like in stain?

A

very light, don’t take up dye

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17
Q

Where are urothelium cells found?

A

urinary blader, ureters, urethra

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18
Q

Where are pseudostratified columnar ciliate cells?

A

position of nuclei vary so it looks like multiple layers but is actually 1 layer
for absorption and secretion, debris and particulate movement

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19
Q

Where are simple squamous epithelial cells found? (5)

A

endothelium, mesothelium, lining alveoli in lungs, loop of henle in kidney, various ducts

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20
Q

What are hemidesmosomes?

A

intercellular junctions that anchor intermediate filaments to basement membrane

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21
Q

What are simple cuboidal cells? What is their function?

A

1 layer thick w/ round nuclei that make a tube

absorption, barrier, secretion

22
Q

What is mesothelium? What is it made of?

A

lining of serous membranes

made of simple squamous epithelia

23
Q

Where are nonkeratinized stratified squamous cells found?

A

oral cavity, portions of pharynx, esophagus, anus, vagina urethra, cornea
basically where there is friction and abrasion not on outermost skin

24
Q

Where are pseudostratified columnar ciliate cells found?

A

lining of nasal cavity, pharynx, trachea, bronchi

25
Q

What are occluding junctions made of?

A

occludins, claudins

26
Q

What are cilia made of?

A

microtubule based

27
Q

What are stereovilli/stereocilia?

A

microvilli of unusual length - long and immotile

28
Q

What are zonula adherens and what do they interact with?

A

type of anchoring junction

connect actin filaments cell to cell

29
Q

What is a serous membrane?

A

epithelial tissue that lines specific internal cavities of body
forms smooth 2 layered membrane
lubricated by fluid derived from serum
mesothelium is part of a serous membrane

30
Q

Where are simple columnar cells found?

A

auditory tubes, uterus, oviducts, stomach, intestines, gallbladder

31
Q

What is special about urothelium cells?

A

dome shaped cells at apical surface

stratified epithelium that allows for stretch and recoil of bladder

32
Q

What is the function of simple columnar cells?

A

absorption and secretion

33
Q

What does the lateral domain of an epithelial cell face?

A

adjacent cells

34
Q

What are anchoring junctions made of?

A

cadherins

35
Q

What are anchoring junctions?

A

lateral adhesions that link into cytoskeleton of adjacent cells
zonula adherens
macula adherens/desmosomes

36
Q

How do apocrine glands secrete?

A

(mammary glands) release of apical portion of cell w/ cytoplasm in plasma membrane

37
Q

Where do you mainly find cilia?

A

in the respiratory tract

38
Q

What are primary cilia?

A

immotile cilia, function as chemosensors, osmosensors, mechanosensors

39
Q

What do serous acini look like in stain?

A

very dark, take up dye heavily

40
Q

What are gap junctions made of?

A

connexin

41
Q

What type of epithelia is one layer thick?

A

simple epithelia

42
Q

What is special about the apical layer of keratinized stratified squamous cells?

A

do not have nuclei

43
Q

what is the basal domain of an epithelial cell to?

A

basal lamina; anchors cell to underlying connective tissue

44
Q

Where are stereovilli/stereocilia restricted to?

A

epididymis and sensory cells of inner ear

45
Q

What is the purpose of microvilli?

A

increase surface area of apical domain by 20-30x –> increase absorption

46
Q

What are microvilli made of?

A

actin core

47
Q

How do holocrine glands secrete?

A

secretion accumulates w/in cell –> apoptosis –> secretion and cell debris released

48
Q

What are macula adherens/desmosomes and what do they interact with?

A

type of anchoring junction

connect intermediate filaments in adjacent cells

49
Q

What are focal adhesions?

A

intercellular junctions that anchor actin filaments to basement membrane

50
Q

What type of epithelia is more than one layer thick?

A

stratified epithelia

51
Q

Where are stratified cuboidal cells found?

A

sweat glands and ducts, ovarian follicles, salivary gland ducts
passageway function is important!