ENERGY & LIFE Flashcards
Metabolism
The sum of all the chemical reactions in the human body
Two major types of metabolic reactions
Endergonic, exergonic
Anabolic reactions are-
Endergonic (require energy)
-DNA replication, transcription, mRNA processing, translation
Catabolic reactions are-
Exergonic (release energy)
-They release energy from food molecules to make ATP & GTP molecules
-Cellular respiration
-Release useful energy that drives anabolic reactions
Anabolic
Small molecules are assembled into large ones. Energy required
Catabolic
Large molecules are broken down into small ones. Energy released
Autotrophs
-Self feeding bc they make carbohydrates directly from CO2
Photosynthetic autotrophs
-Capture sunlight and use its energy to make energy rich ATP & NADPH molecules (these molecules energize the enzymes that convert CO2 to carbohydrate)
Some autotrophs use ______ to convert CO2 molecules into carbohydrates
Chemosynthesis
-They use inorganic chemicals such as H2S, H2, to make the energy rich ATP & NADH molecules that energize the enzymes that convert the CO2 molecules into carbs
Heterotrophs
-Feed on others
-Species that cannot perform photosynthesis or chemosynthesis
-They must eat autotrophs & other heterotrophs to obtain food
-They require an external source of food molecules
All cells use _____ to fuel endergonic reactions
ATP & GTP
What bond in ATP & GTP stores useful energy?
The PO4 to PO4 bond
What molecules supply the energy to make ATP & GTP
Food molecules
ATP is a _______ molecule
Signaling
ATP is the ____ in RNA
“A”
GTP is the ___ in RNA
“G”
Cells use ______ ________ to release and capture the energy stored in the PO4-PO4 bond of ATP
ATPase enzymes
ATPases add a ____ molecules to the bond between the 2nd & 3rd PO4 groups of ATP to hydrolyze ATP
H20
ATPases linked the released energy to
Endergonic reactions
ATPase enzymes require _____ ions as a _____ to hydrolyze the ATP molecule
Magnesium, cofactor
-The enzyme is inactive w/out Mg cofactor
-Mg ions are cofactors for ~300 cellular reactions
Cells require a continuous supply of ___ molecules to satisfy their significant energy demands
ATP
-Each human cells consumes > billion ATP molecules/second
-Each ATP molecule is consumed & resynthesized ~10,000x daily
-The human body contains ~50-250 grams of ATP molecules at any point in time
The circulatory system continuously delivers the raw materials (O2, glucose) that your cells need to make ___ so you can live
ATP
-Your cells must constantly synthesize ATP to satisfy their energy demands
What are the 3 locations where eukaryotic cells synthesize ATP?
-Cytosol (glycolysis)
-Mitochondrion (requires O2)
-Nucleus (NUDIX5 enzyme converts ADP-Ribose to ATP)
All cells must complete each _____ reaction to an _____ reaction that releases energy
Endergonic to exergonic