CELL MEMBRANE TRANSPORT Flashcards

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1
Q

The cell membrane enables

A

Life to exist

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2
Q

Components of the cell membrane

A

-Phospholipids
-Steroids (cholesterol)
-Extrinsic membrane proteins
-Intrinsic membrane proteins

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3
Q

Cell membrane functions

A

-Import and export of all required substances
-Cell signaling
-Cell to cell recognition/interactions
-Maintains a voltage in cells
-Cell to cell binding and cell to extracellular matrix binding

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4
Q

The ER and golgi apparatus

A

Possess enzymes that synthesize phospholipids and steroids that form cell membranes

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5
Q

The golgi apparatus uses

A

Vesicles to deliver new membrane materials to the cell membrane

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6
Q

Vesicles fuse with the

A

Cell membrane to increase its size

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7
Q

The _______ neutrality of small hydrophobic and nonpolar molecules enables them to pass directly through the hydrophobic interior of the cell membrane

A

Electric

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8
Q

_______ supplies the energy that drives their transport

A

Diffusion

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9
Q

Many small, polar, hydrophilic atoms and molecules must cross the ____ _________ to maintain cell function

A

Cell membrane

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10
Q

What small, polar, hydrophilic atoms and molecules must cross the cell membrane to maintain cell function?

A

-Electrically charged ions (Calcium, Chloride)
-Water molecules
-Glucose, amino acids, nucleotides
-Their hydrophilic properties prevent their direct passage through the hydrophobic interior of the cell membrane

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11
Q

The facilitated diffusion of small hydrophilic ions and water molecules requires

A

Channel proteins

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12
Q

Channel proteins in the cell membrane have a

A

Hollow interior (channel)
Channel diameter is larger than ion and H20 diameter

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13
Q

The cell membrane contains

A

> 300 types of channel proteins

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14
Q

________ enable H20 molecules to cross cell membranes

A

Aquaporins (water porous)

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15
Q

Channel proteins _______ the diffusion

A

Facilitate

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16
Q

________ proteins enable the facilitated diffusion of small hydrophilic molecules, except for H20, across the cell membrane

A

Carrier

17
Q

These molecules are too large to pass through _______ proteins

A

Channel
-They require carrier proteins to “carry” them across the membrane

18
Q

Each carrier protein transports

A

~100-1000 molecules per second

19
Q

Active transport

A

Requires chemical energy
Move small hydrophilic atoms and small molecules across the cell membrane from lower to higher concentration

20
Q

Active transport proteins

A

Carrier proteins or ion pumps

21
Q

Some cancer cells are drug resistant due to

A

Drug export

22
Q

The function of mutli-drug resistance proteins is to

A

Export potentially toxic molecules before they harm the cell

23
Q

Multi-drug resistance proteins also enable

A

-Cancer cells to export cancer drugs
-Antibiotic resistant pathogenic bacteria to export antibiotic molecules