Endocrine - Hormones Flashcards
What hormones are produced in the Hypothalamus?
TRH
Dopamine
CRH
GnRH
GHRH
SS
What hormones are produced in the Anterior Pituitary?
FSH
LH
ACTH
TSH
Prolactin
GH
FLAT PIG
What hormones are produced in the Posterior Pituitary?
ADH
Oxytocin
What hormones are produced in the Thyroid?
T3
T4
rT3
What hormones are produced in the Parathyroid?
PTH
What hormones are produced in the Adrenal Cortex?
Cortisol
Aldosterone
Androgens
What hormones are produced in the Adrenal Medulla?
Epi
NE
What hormones are produced by the Pancreas?
Insulin
Glucagon
Somatostatin
What hormones are produced by the Ovaries?
Estradiol
Progesterone
Inhibin
What hormones are produced by the Testes?
Testosterone
Inhibin
What hormones are produced by the Liver?
IGF-1
What is the function of TRH?
Stimulates release of TSH from the anterior pituitary
What stimulates the release of TRH from the hypothalamus?
Cold
Stress
Exercise
What inhibits the release of TRH from the hypothalamus?
↑T3 & T4
What happens if you have too much TRH release?
Hyperthyroidism
What occurs if there is not enough TRH release?
Hypothyroidism
What is the function of Dopamine?
Inhibit GH release from the Anterior Pituitary
Inhibits prolactin release from the Anterior Pituitary
What stimulates release of Somatostatin?
Nutrient Ingestion
ACh
Secretin
What inhibits release of Somatostatin?
NE
What occurs if there is too much Somatostatin?
Reduction in secretion of endocrine hormones
What occurs if there is not enough Somatostatin?
Increases secretion of endocrine hormones
What is the function of Somatostatin?
Inhibits ACTH, TSH, GH, Cortisol, and Insulin
What is the function of CRH?
Stimulate secretion of ACTH and POMC
What stimulates the release of CRH?
Stress
Low blood cortisol
Hypoglycemia
What inhibits the release of CRH?
Glucocortioids (negative feedback of cortisol)
What occurs if there is too much CRH?
Increased cortisol production
Immune suppression
Mood dysfunction
Insomnia
What occurs if there is not enough CRH release?
Adrenal insufficiency (Addison’s Disease) - adrenal glands are damaged or destroryed
Problem with pituitary or hypothalamus
What is the function of GHRH?
Stimulate release of GH
What stimulates release of GHRH?
Hypoglycemia
SNS stimulation
Stress
Exercise
What inhibits release of GHRH?
Somatostatin
What occurs if there is too much GHRH release?
Acromegaly
What occurs if there is not enough GHRH release?
Short Stature
Dwarfism
What is the function of GnRH?
Stimulate release of FSH and LH
What stimulates release of GnRH?
ACh
Dopamine
Estrogen
Testosterone
What inhibits the release of GnRH?
Prolactin
High estrogen and testosterone
What occurs if there is too much GnRH released?
↑Risk of pituitary adenoma
Excessive LH and FSH secretion
Infertility
What occurs if there is not enough GnRH released?
Failed/delayed puberty
Infertility
↓LH and FSH secretion
ED
What is the function of FSH?
Stimulates hormone release from gonads
Stimulates follicular development and spermatogenesis
What stimulates release of FSH?
GnRH
What inhibits release of FSH?
Estrogen
Inhibin
What occurs if there is too much FSH?
Infertility
Irregular periods
early/delayed puberty
What occurs if there is not enough FSH release?
Poor ovarian function
Infertility
loss of bone density
What is the function of LH?
Stimulates hormone release from gonads
Stimulates ovulation
What stimulates release of LH?
GnRH
What inhibits release of LH?
Estrogen and testosterone negative feedback
inhibin
What occurs if there is too much release of LH?
Delayed puberty
Infertility
What occurs if there is not enough release of LH?
Infertility
Irregular periods
early/delayed puberty
What is the function of ACTH?
Stimulates adrenal cortex hormone release
synthesis of cortiso,l adrenal androgens, and slightly aldosterone
What stimulates release of ACTH?
CRH
stress
↓Cortisol
Hyperglycemia
Sleep/wake cycle
ADH
What inhibits release of ACTH?
Somatostatin
Negative feedback from cortisol
What occurs if there is too much ACTH?
Cushing’s Syndrome
↑Cortisol
Hyperpigmentation
What occurs if there is not enough ACTH?
↓Secretion of Adrenal Hormones
Adrenal insufficiency - Addison’s Disease
What is the function of TSH?
Synthesis of T3/T4
Major stimulator of Thyroid Hormone secretion
Growth and vascularity of thyroid gland
What stimulates release of TSH?
TRH
What inhibits release of TSH?
Somatostatin