Endocrine Disorders Flashcards
1
Q
Presence of C Chain
A
part of insulin production- T2D
2
Q
GLUT2
A
transports glucose into B cells
3
Q
MoA of Insulin
A
binds to receptor tyrosine kinase
receptors phosphorylate themselves and IRS-1 and GLUT4
4
Q
Effects of Insulin
A
decrease glucose, fat, AA in blood
5
Q
GLUT4
A
causes glucose to be taken up into cell
6
Q
Normal Fasting Blood Glucose Levels
A
70-100
7
Q
Prediabetic Fasting Blood Glucose Levels
A
100-125
8
Q
Diabetic Fasting Blood Glucose Levels
A
125+
9
Q
T1D
A
destruction of B cells- no insulin production
muscle wasting
lifelong insulin therapy
10
Q
T2D
A
loss of insulin sensitivity from chronic high levels of glucose
Metformin
11
Q
T3/T4
A
bone growth CNS maturation increase heat production increase metabolism increase CO
12
Q
Hyperthyroidism
A
too much T3/T4 weight loss w/ increased appetite heat intolerance exophthalmos goiter
13
Q
Treating Hyperthyroidism
A
remove tumor
14
Q
Example of Hyperthyroidism
A
Grave’s Disease
15
Q
Hypothyroidism
A
not enough T3/T4 weight gain cold intolerance mental slowness myxedema
