Dermatopathology 2

Question 1

Impetigo

Answer 1

honey colored lesions

Question 2

Causes Impetigo

Answer 2

Staph aureus

group A beta-hemolytic strep

Question 3

Group most likely to be affected by impetigo

Answer 3

preschoolers

Question 4

Impetigo Contagiosa

Answer 4

crusty pustules

Question 5

Impetigo Bullosa

Answer 5

bulla

S. aureus

Question 6

Blister formation in impetigo

Answer 6

bacteria make toxin that cleaves desmoglein- adheres epithelial cells

Question 7

Ecthyma

Answer 7

deeper infection of impetigo

erosion of dermis

Question 8

Treating Impetigo

Answer 8

oral antibiotic

antibiotic ointment

Question 9

Folliculitis

Answer 9

staph infection of hair follicle

Question 10

Furuncule

Answer 10

setting of folliculitis

firm nodule that develops an abscess

Question 11

Clearing Furuncle

Answer 11

neutrophils

also damages tissue

Question 12

Carbuncle

Answer 12

multiple combined furuncles

subcutaneous abscesses, superficial pustules, draining pus

Question 13

Erysipelas

Answer 13

beta-hemolytic strep infect skin and spread along superficial lymph vessels

Question 14

Psoriasis

Answer 14

not itchy

affects elbows, knees, scalp, groin

Question 15

Diseases associated with psoriasis

Answer 15

psoriatic arthritis

AIDS- face

Question 16

Lesions of Psoriasis

Answer 16

pink/ salmon colored

covered with silver/ white loose scales

Question 17

Formation of Psoriasis

Answer 17

increased epidermal cell turnover leads to acanthosis (epidermal thickening)

Question 18

Pathogenesis of Psoriasis

Answer 18

HLA-C

CD4 calls in CD8

Question 19

Seborrheic Dermatitis

Answer 19

in areas with lots of sebaceous glands

dandruff

Question 20

Cradle Cap

Answer 20

infantile presentation of seborrheic dermatitis

treat with olive oil

Question 21

Lichen Planus

Answer 21

pruritic, purple, polygonal papules; dendritic

resolve spontaneously after 1-2 years

Question 22

Pemphigus vulgaris

Answer 22

> 40 yoa
mucosa and skin (especially face)
vesicles and bulla that rupture easily- crust

Question 23

Pemphigus vulgaris attack strategy

Answer 23

target desmogleins

IgG in fish net pattern

Question 24

Bullous pemphigoid

Answer 24

in elderly

do not rupture easily

Question 25

Bullous pemphigoid morphology

Answer 25

covers entire epidermis and lifts it up

causes nonacantholytic blisters

Question 26

Bullous pemphigoid antigens and antibodies

Answer 26

proteins in hemidesmosomes

antibodies deposit linearly along BM

Question 27

Acne vulgaris

Answer 27

disorder of sebaceous follicles

during adolescence

Question 28

Mechanism of Acne vulgaris

Answer 28

androgenic hormones cause abnormal keratinization of follicles

Question 29

Open Comedones

Answer 29

blackheads

Question 30

Closed Comedones

Answer 30

whiteheads

Question 31

Propionibacterium acnes

Answer 31

bacterial lipases convert lipids in sebum to pro inflammatory fatty acids

Question 32

Sequelae

Answer 32

on trunk
heal with pitted scars on face and hypertrophic scars on back
postinflammatory hyperpigmentation

Question 33

Rosacea

Answer 33

lack comodones

blepharoconjunctivitis

Question 34

Causes Rosacea

Answer 34

sun exposure
excessive face washing
irritating cosmetics

Question 35

Rhinophyma

Answer 35

enlarged red nose

normally in middle aged men with rosacea

Question 36

Prerosacea

Answer 36

facial erythema and telangiectasia

“rosy cheeked”

Question 37

Vitiligo

Answer 37

loss of melanocytes

tanning makes more pronounced

Question 38

Melasma

Answer 38

enhanced pigment transfer from melanocytes
associated with pregnancy and oral contraceptives
worsened with sunlight

Question 39

Lentigo

Answer 39

cafe au lait spots

does not darken in sunlight

Question 40

Too many Cafe au lait spots can be a sign of…..

Answer 40

neurofibromatosis type 1

Question 41

Solar Lentigo

Answer 41

develop with age and sun exposure