Dermatopathology

Question 1

Macule

Answer 1

flat lesion < 1 cm

Question 2

Patch

Answer 2

macule > 1 cm

Question 3

Papule

Answer 3

elevated solid skin lesion < 1 cm

Question 4

Plaque

Answer 4

papule > 1 cm

Question 5

Vesicle

Answer 5

small fluid filled blister < 1 cm

Question 6

Bulla

Answer 6

large fluid filled blister > 1 cm

Question 7

Pustule

Answer 7

vesicle containing pus

Question 8

Wheal

Answer 8

transient smooth papule or plaque

Question 9

Scale

Answer 9

flaking off of stratum corneum

Question 10

Crust

Answer 10

dry exudate

Question 11

Molluscum contagiosum

Answer 11

viral
normally asymptomatic
umbilicated papules- pearly/ waxy w/ sunken centers; in clusters

Question 12

People most likely to have molluscum contagiosum

Answer 12

children
sexually active
worse effects in immunosuppressed- unilateral conjunctivitis

Question 13

Signs that molluscum contagiosum is healing

Answer 13

erythema- redness around lesion site

Question 14

Clearance time for molluscum contagiosum

Answer 14

6 months

Question 15

HPV

Answer 15

everywhere; subclinical
warts
produce carcinoma

Question 16

Types of cancer caused by HPV

Answer 16

carcinoma in situ (CIS)

squamous cell carcinoma

Question 17

Verruca vulgaris

Answer 17

very common- kids
resolve spontaneously
skin to skin transmission
epidermis

Question 18

Clinical presentation of Verruca vulgaris

Answer 18

black dots

lots of keratin

Question 19

Types of HPV causing conjunctival papilloma

Answer 19

6 and 11

Question 20

Most likely place for conjunctival papilloma

Answer 20

palpebral conjunctiva

Question 21

Herpes Simplex Virus

Answer 21

grouped vesicles w/ erythematous base
most have no symptoms
lies in peripheral sensory nerves

Question 22

HSV-1 Location

Answer 22

above neck

Question 23

HSV-2 Location

Answer 23

below waist

Question 24

HSV Recurrence

Answer 24

can impact any region that is innervated by infected nerve, not just at site of infection

Question 25

HSV Signs/ Symptoms

Answer 25

tingling, pain, burning, itching
red papules
fragile vesicles that rupture

Question 26

Most common sites of primary infection of HSV

Answer 26

mouth, anogenitalia, hands

Question 27

HSV Ocular

Answer 27

dendritic keratitis

Question 28

Treating HSV

Answer 28

oral antivirals

Question 29

Initial infection of Varicella Zoster Virus

Answer 29

children

airborne and direct contact

Question 30

Urticaria

Answer 30

hives/ wheals

develop/ fade within hours

Question 31

Causing Urticaria

Answer 31

localized mast cell degranulation causes decreased dermal microvascular permeability which causes wheals

Question 32

Eczema

Answer 32

red, oozing, crusted lesions that develop into raised, scaling plaques

Question 33

Example of Allergic Contact Dermatitis

Answer 33

poison ivy

Question 34

Urushiol

Answer 34

Ag responsible for poison ivy reaction

Question 35

Phytodermatitis

Answer 35

caused by furocoumarin chemicals in plants and exposure to UV A

Question 36

Difference b/t eczema and hives

Answer 36

E- epidermis, more likely to rupture

H- dermis, less likely to rupture