Endocrine Flashcards
phenylketonuria (PKU)
Absence of phenoalanine hydroxylase enzyme
dx PKU
Newborn screening’s
tx PKU
diet free in Meat, Limited fruits/veggies and grains
phenylalanine free formula
breast feed
Galactosemia
Lack of enzyme that converts galactose to glucose
Lactose intolerant
tx galactosemia
Lactose free diet
Soy formula
Calcium supplements
No breast-feeding
which medication should you be cautious in taking with galactosemia?
Penicillin
Some vitamins
what is the number one concern with hypothyroidism
Airway protection
tx hypothyroidism
Oral thyroid hormone replacement for life
Synthroid
med. Administration precautions.
Avoid heat exposure
Don’t mix with soy formula
treatment for hyperthyroidism
propylthiouracil
Subtotal thyroidectomy
High calorie diet
Limit activities/stress
what is a complication from PTU
agranulocytosis/leukopenia
Sore throat and fever
what should be done with agranulocytosis?
Placed in isolation and start antibiotics
where does the growth hormone deficiency condition occur?
Anterior pituitary
Hypofunction
sx growth hormone deficiency
skeletal proportions are normal for age
Retarded bone age
tx growth hormone deficiency
Daily sub Q injection’s
very expensive
Cortisone
when should the injections be taken throughout the day?
At night
Mimics natural tendency
Will children be giants after growth hormone injections
No, reassure parents
precocious puberty
Before nine in boys
Before eight in girls
True precocious puberty
normal puberty but earlier
pseudo, precocious puberty
Thelarche – early breast
Pubarche – early pubic, under arm hair
Menarche - period
what is the treatment for precocious puberty?
Monthly injection of Lupron
Take until normal age of starting puberty