Emma1 Flashcards

1
Q

haematopoiesis

A

commitment and differentiation processes that lead to the formation of all blood cells from haematopoietic stem cells

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2
Q

function of red blood cells

A

carry O2 and CO2

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3
Q

function of plasma

A

carry nutrients

carry messages

carry waste

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4
Q

function platelets and clotting factors

A

prevention of leaks

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5
Q

function of anticoagulants

A

prevention of blockages

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6
Q

function of fibrinolytics

A

prevention of blockages

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7
Q

function of granulocytes and monocytes

A

phagocytosis and killing

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8
Q

function of lymphocytes

A
  • antigen recognition

- antibody formation

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9
Q

polycythaemia

A

disease state in which the hematocrit is elevated.

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10
Q

haematocrit

A

volume percentage of red blood cells in the blood

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11
Q

haematinics

A

vitamins and minerals required for normal erythropoiesis

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12
Q

erythropoiesis

A

process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell.

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13
Q

whats an erythrocyte

A

red blood cell

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14
Q

where are platelets produced

A

liver

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15
Q

what are romiplostim and eltrombopag

A

platelet making agonists that can be used therapeutically

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16
Q

thrombocytosis

A

disorder in which body produces too many platelets

17
Q

thrombocytopenia

A

condition in which you have a low platelet count

18
Q

causes of thrombocytopenia

A

marrow failure

immune destruction

19
Q

medications that can cause altered function of platelets

A

aspirin

clopidogrel

abciximab

20
Q

neutrophil function

A

to ingest and destroy pathogens

21
Q

neutrophil speed of response

A

1-2 hours

22
Q

neutrophilia

A

increase in circulating neutrophil count

23
Q

neutropenia

A

decrease in circulating neutrophil count

24
Q

causes of neutropenia

A

drugs

marrow failure

sepsis

autoimmune

25
Q

opsonisation

A

molecular mechanism whereby molecules, microbes, or apoptotic cells are chemically modified to have a stronger attraction to the cell surface receptors on phagocytes and NK cells

26
Q

where are T cells produced and matured

A

produced - bone marrow

matured - thymus

27
Q

where are B cells produced and matured

A

bone marrow

28
Q

causes of lymphocytosis

A

infectious mononucleosis

pertussis (whooping cough)

29
Q

another name for pertussis?

A

whooping cough

30
Q

causes of lymphopenia

A

usually post-viral

lymphoma

31
Q

function of type 1 human leucocyte factor (HLA)

A

displays internal antigens on all nucleated cells

32
Q

function of type 2 human leucocyte factors (HLA)

A

displays antigens eaten by professional antigen presenting cells

33
Q

paraprotein

A

protein found in the blood only as a result of cancer or disease