13 Flashcards

1
Q

serum ferrtin indicates

A

body iron store levels

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2
Q

what does a low reticulocyte count indicate

A

aplastic anaemia

bone marrow tumour

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3
Q

aplastic anaemia

A

serious condition affecting the blood, where the bone marrow and stem cells do not produce enough blood cells. It is also called bone marrow failure and can happen suddenly (acute) or develop over a period of time (chronic).

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4
Q

function reticulocyte count

A

tell you if bone marrow working properly

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5
Q

causes normochromic normocytic anaemia

A
  • acute blood loss
  • haemolysis
  • secondary anaemia
  • hypoplasia
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6
Q

define hypochomic microcytic anaemia

A

cells are small and pale

low MCV and MCH

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7
Q

what is A antigen made of

A

N-acetyl-galactosamine

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8
Q

what is B antigen made of

A

galactose

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9
Q

congenital causes haemolytic anaemia

A
  • hereditary spherocytosis
  • G6PD deficiency
  • haemoglobinopathy
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10
Q

DAGT

A

direct antoiglobulin test

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11
Q

investigations haemolytic anaemia

A

blood film
FBC
reticulocyte count
serum bilirubin

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12
Q

for FFP, what group can A have

A

A and AB

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13
Q

signs of bone marrow failure

A
  • anaemia
  • infections
  • hypercalcaemia
  • renal failure
  • bone disease
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14
Q

signs of bone disease

A
anaemia 
patholgical fractures
hypercalcaemia
cord compression
lytic bone lesions
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15
Q

investigations if Wells score high/ D-dimer +

A
  • doppler of leg
  • CTPA
  • CT venogram
  • VQ scan
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16
Q

lab testing if Wells score low

A

d dimer

17
Q

predicted investigation results in ALL

A

haemoglobin low
WCC high
platelets low
bone marrow 90% B lymphoblasts

18
Q

define type 1 vWD

A

quantitive deficiency

19
Q

presentation essential thrombocythaemia

A
symptoms of arterial and venous thrombosis
digital ishcaemia 
gout
headache
mild splenomegaly
20
Q

where are B cells produced and matured

A

bone marrow

21
Q

haemorrhagic diathesis

A

unusual susceptibility to bleed

22
Q

management of DIC in a patient if not actively bleeding

A

low doses of anticoagulation