13 Flashcards
serum ferrtin indicates
body iron store levels
what does a low reticulocyte count indicate
aplastic anaemia
bone marrow tumour
aplastic anaemia
serious condition affecting the blood, where the bone marrow and stem cells do not produce enough blood cells. It is also called bone marrow failure and can happen suddenly (acute) or develop over a period of time (chronic).
function reticulocyte count
tell you if bone marrow working properly
causes normochromic normocytic anaemia
- acute blood loss
- haemolysis
- secondary anaemia
- hypoplasia
define hypochomic microcytic anaemia
cells are small and pale
low MCV and MCH
what is A antigen made of
N-acetyl-galactosamine
what is B antigen made of
galactose
congenital causes haemolytic anaemia
- hereditary spherocytosis
- G6PD deficiency
- haemoglobinopathy
DAGT
direct antoiglobulin test
investigations haemolytic anaemia
blood film
FBC
reticulocyte count
serum bilirubin
for FFP, what group can A have
A and AB
signs of bone marrow failure
- anaemia
- infections
- hypercalcaemia
- renal failure
- bone disease
signs of bone disease
anaemia patholgical fractures hypercalcaemia cord compression lytic bone lesions
investigations if Wells score high/ D-dimer +
- doppler of leg
- CTPA
- CT venogram
- VQ scan