3 Flashcards
1
Q
presentation haemophilia A/B
A
- bruise easily
- nose bleeds
- bleed easily after procedures e.g. teeth removed
- haemoarthrosis
- CNS bleeding
- retroperitoneal bleeding
2
Q
what is haemophilia A
A
missing/ defective factor VIII
3
Q
causes haemorrhagic diathesis
A
- haemophilia A/B
- vWD
- platelets low
- coag factors low
4
Q
thromboembolism
A
clot movement along blood vessel
5
Q
what does IgE do
A
- parasite immune response
- hypersensitivity
6
Q
what does IgA do
A
mucous membrane immunity
7
Q
causes lymphopenia
A
- post viral
- lymphoma
8
Q
causes lymphocytosis
A
- ALL
- CLL
- hep A/B/C
- hypothyroidism
- infectious mononucleosis
- pertussis
9
Q
lymphocytosis
A
higher-than-normal amount of lymphocytes
10
Q
where are T cells produced and matures
A
produced bone marrow
matured @ thymus
11
Q
types of T cell
A
- cytotoxic
- helper
- regulatory
12
Q
B cell function
A
memory of foreign antigens
make antibodies
13
Q
causes neutropenia
A
- drugs
- marrow failure
- sepsis
- autoimmune
- chronic granulomatous disease
14
Q
when will G-CSF be used therapeutically
A
- neutropenia
- for the mobilisation of stem cells
15
Q
what is G-CSF
A
glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream
