15

Question 1

blood group B have antibodies against

Answer 1

A

Question 2

hodgkin lymphoma investigations

Answer 2

blood film
bone marrow biopsy
lymph node biopsy
FBC
PET scan
CT
MRI
CXR

Question 3

describe high grade Non-hodgkins lymphoma

Answer 3

diffuse large B cell
aggressive, fast growing
can be cured

Question 4

management hodgkin lymphoma

Answer 4

combination of chemo and radio therapy
monoclonal antibodies
immunotherapy

Question 5

describe low-grade lymphoma

Answer 5

follicular, marginal zone
leave alone if causing problems
often asymptomatic
can’t be cured

Question 6

management non-hodgkin lymphoma

Answer 6

combination chemo

Question 7

what temp red blood cells kept at

Answer 7

4*c

Question 8

lymphoma

Answer 8

cancer of lymphoid origin

Question 9

what does presence of paraprotein indicate

Answer 9

monoclonal proliferation of B cell/ plasma cells somewhere in the body
only found in presence of malignancy/ disease

Question 10

what is involved in a screening for blood donors

Answer 10

sex
age
travel
tattoos
ABO
Hep B/C/E
HIV
syphilis

Question 11

what does IgM paraprotein presence indicate

Answer 11

lymphoma

Question 12

what does IgG, IgA paraprotein presence indicate

Answer 12

myeloma

Question 13

indications for red cell transfusion

Answer 13

1. correct severe anaemia
2. improve QOL in uncorrectable anaemia
3. prepare patient for surgery/ speed up recovery
4. reverse damage caused in sickle cell for example

Question 14

TACO

Answer 14

transfusion associated circulatory overload

Question 15

TRALI

Answer 15

transfusion relate acute lung injury

Question 16

ATR

Answer 16

acute transfusion reaction e.g. allergic, febrile

Question 17

function electrophoresis

Answer 17

assesses antibody diversity

identifies paraprotein