14 Flashcards
management pyrexia following transfusion
anti-pyretic drugs
ALL investigations
- bone marrow biopsy
- blood films
- FBC
- U+Es
- LFTs
- CXR
- CT
- LP
- PCR
- lymph node biopsy
management of reducing risk of sepsis in haematological malignancy
- ciprofloxacin
- fluconazole
- aciclovir
- co-trimoxazole
- stem cell rescue/ transplant
- protective environment (laminar flow room)
- IV immunoglobulin replacement
- vaccination
presentation neutropenic sepsis
- fever with no localsising signs
- rigors
- chest infection/ pneumonia
- cellultiis
- UTI
- septic shock
allopurinol
used for correcting hyperuricaemia
leukapheresis
lab procedure in which WBCs are separated from a sample of blood
what is involved in a group and save
blood group
atypical red cell antibody screen
composition arterial thrombus
platelets and fibrin
white clot
what triggers immune haemolysis warm antibody
autoimmune
drugs
CLL
sources of stem cells for transplantation
bone marrow
umbilical cord blood
what are used for treating acute graft rejection
monoclonal antibodies against Il2 receptors
basiliximab and daclizumab
cyclosporine
methotrexate
common associations with immune thrombocytopenia purpura
EBV HIV collagenosis lymphoma drug abuse
pattern of bleeding vWD
- mucosal
- epistaxis
- bruises
- purpura/ petichiae
- bruises
- menorrhagia
- GI
presentation primary immunodeficiency
- lots of infections URI
- antibody deficiency
- increase in fungal infections
- reactivation of latent herpes
- recurrent candida
describe acute transplant rejection
recipient has pre made antibodies against that HLA type
