Electrophysiology WK5 L1 Flashcards

1
Q

WHAT IS ELECTRICAL POTENTIAL?

A
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2
Q

WHAT IS THE ELECTRICAL CURRENT?

A

THW FLOW OF THE CHARGED PARTICLES FROM ONE POINT TO ANOTHER

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3
Q

ARE LIVING CELLS POLARIZED?

A

YES

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4
Q

WHAT IS THE RESTING MEMBRANE POTENTIAL?

A

-70 mV WITH A NEGATIVE CHARGE ON THE INSIDE OF THE MEMBRANE WHEN THINGS ARE AT REST

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5
Q

IS THE MEMBRANE VERY PERMIABLE TO K+ OR Na-?

A

K+

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6
Q

WHAT DOES THE SODIUM (Na-) / POTASSIUM (K+) PUMP DO WHEN IT IS AT REST?

A

PUMPS PUT 3X Na- FOR EVERY 2X K+ IT BRINGS IN USING ATP

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7
Q

WHAT IS LOCAL POTENITALS?

A

SMALL CHANGE IN VOLTAGE ALONG ONE SPOT IN THE MEMBRANE

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8
Q

WHEN DOES LOCAL POTENTIALS OCCUR?

A

WHEN NEURONS ARE STIMULATED BY CHEMICALS - LIGHT - HEATS - MECHANICAL DISTURBANCES

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9
Q

WHAT IS THE CHANGE IN VOLTAGE CALLED?

A

DEPOLARISATION

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10
Q

WHAT IS DEPOLARISED?

A

MOVING TOWARDS 0 (EQUAL CHARGED) FROM A HIGHER CHARGE LEVEL

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11
Q

WHAT IS POLARISED?

A

MOVING AWAY FROM 0 (EQUAL CHARGE) TO A HIGHER CHARGE

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12
Q

HOW DOES DEPOLARISATION DECREASE POTENTIAL?

A

SODIUM CHANNELS OPENING SO SODIUM CAN CROSS THE MEMBRANE FROM HIGH TO LOW CONCENTRATION

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13
Q

WHEN ARE THE SODIM CHANNELS CLOSED?

A

AT REST

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14
Q

WHAT IS ACTION POTENTIAL?

A

CHANGE IN THE VOLTAGE INT HE MEMBRANE AT A LOCAL SPOT

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14
Q

WHAT IS ACTION POTENTIAL?

A

CHANGE IN THE VOLTAGE IN THE MEMBRANE AT A LOCAL SPOT CAUSING DEPOLARIZATION AND REPOLARIZATION

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15
Q

WHAT IS THE THRESHOLD POINT?

A

-55 mV

16
Q

WHAT HAPPENS WHEN WE MEET THE THRESHOLD VOLTAGE?

A

LOTS OF SODIUM CHANNELS OPEN AND MASSIVE AMOUNTS OF SODIUM RUSH INTO THE CELL MAKING THE CELL MORE POSITIVELY CHARGED

17
Q

WHAT IS REPOLARIZATION?

A

WHEN THE POTASSIUM CHANNELS SLOWLY OPEN RELEASING POTASSIUM OUT OF THE CELL WHICH MAKES THE CELL MORE NEGATIVELY CHARGED

18
Q

WHAT IS HYPER-POLARIZATION?

A

WHEN THE POTASSIUM CHANNELS RELEASE SO MUCH SODIUM OUT OF THE CELL LEAVING THE CELL MORE NEGATIVELY CHARGED THAN IT WAS PREVIOUSLY

19
Q

WHAT IS THE REFRACTORY PERIOD?

A

THE PERIOD OF RESISTANCE TO STIMULATION (COOL DOWN PERIOD BETWEEN ACTION POTENTIALS)

20
Q

WHAT IS THE ABSOLUTE REFRACTORY PERIOD?

A

PERIOD WHERE THE SODIUM CHANNELS CLOSE DURING DEPOLARIZATION AND WILL NOT START AN ACTION POTENTIAL NO MATTER HOW MUCH STIMULI IS GIVEN

21
Q

WHAT IS THE RELATIVE REFRACTORY PERIOD?

A

STIMULUS CAN CREATE AN ACTION POTENTIAL IF THE POTASSIUM CHANNELS ARE OPEN

22
Q

WHAT IS AN INHIBITRY SYNAPSE?

A

WHEN CHLORIDE ANIONS MOVE INTO THE CELL MAKING IT MORE NEGATIVELY CHARGED AND HYPERPOLARIZING THE CELL

23
Q

WHAT ARE THE STEPS OF CESSATION OF SIGNAL

A

DIFFUSION - ENZYMATIC DEGRADATION - REUPTAKE OF NEUROTRANSMITTER

24
Q

WHAT IS DIFFUSION?

A

SOME OF THE NEURTOTRANSMITTER MOLECULES DIFUSE AWAY FROM SYNAPTIC CLEFT

25
Q

WHAT IS ENZYMATIC DEGRADATION?

A

ENZYMES BREAK DOWN NEUROTRANSMITTERS

26
Q

WHAT IS REUPTAKE OF NEUROTRANSMITTERS?

A

MANY NEUROTRANSMITTERS ARE ACTIVELY TRANSPORTED BACKT O THE PRESYNAPTIC NEURON BY ENDOCYTOSIS

27
Q

WHAT ARE THE TYPES OF NEUROTRANSMITTERS?

A

ACETYCHLOLINE - AMINO ACID NEUROTRANSMITTERS - MONOAMINES - NEUROPEPTIDES

28
Q

WHAT IS ACETYCHLOLINE?

A

NEURO TRANSMITTERS FOR THE MUSCLES AND PERIPHERAL NERVOUS SYSTEM

29
Q

WHAT ARE AMINO ACID NEUROTRANSMITTERS?

A

NEUROTRANSMITTERS IN THE BRAIN - EXCITATORY (GLUTAMATE) AND INHIBITORY (GABBA)

30
Q

WHAT ARE MONOAMINES?

A

MODIFIED AMINO ACIDES

31
Q

WHAT ARE NEUROPEPTIDES?

A

PROTEIN NEUROTRANSMITTERS IN THE NERVOUS SYSTEM