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Farmacología > Digestivo: antidiarréicos > Flashcards

Digestivo: antidiarréicos Flashcards

1
Q

2 grupos de antidiarreicos

A

Absorbentes y Opioides

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2
Q

Cómo funcionan los antidiarreicos absorbentes?

A

Unen a las toxinas que causan diarrea y actúan en células del TGI

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3
Q

2 fármacos importantes antidiarreicos absorbentes

A

Subsalicilato de Bismuto y Caolin - pectina

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4
Q

MoA del Subsalicilato de Bismuto

A

efectos antisecretores, antiinflamatorios y antimicrobianos

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5
Q

Indicaciones del Subsalicilato de Bismuto

A

tx de diarrea aguda, del viajero y episódica

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6
Q

EA del Subsalicilato de Bismuto

A

ototoxicidad, heces obscuras, Sx Reye

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7
Q

MoA del Caolin-Pectina

A

adhieren a toxinas bacterianas y evitan su absorción en mucosa

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8
Q

Indicaciones del Caolin-pectina

A

tx de diarrea aguda, del viajero y episódica

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9
Q

ADME del Caolin-pectina

A

evitar consumo 2-3h con otro fármaco para evitar malabsorción

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10
Q

EA del Caolin-pectina

A

náuseas, vómito, dolor abdominal

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11
Q

Cómo funcionan los antidiarreicos opioides?

A

Unen a receptores opioides intestinales y bajan peristaltismo

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12
Q

Opioide antidiarreico más usado

A

Loperamida

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13
Q

MoA de la Loperamida

A

Une a receptores opioides intestinales y baja peristaltismo

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14
Q

Indicaciones de la Loperamida

A

tx de diarrea aguda y crónica

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15
Q

EA de la Loperamida

A

Inespecíficos + angioedema, erupciones y boca seca

Dosis altas? Torsades de Pointes

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16
Q

Cuándo se contraindica la Loperamida?

A

En diarreas infecciosas

Farmacología (37 decks)

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