Diagnosis and management of Gastrointestinal disorders Flashcards
Peptic Ulcer Disease
Cause/ Incidence:
1. ___ ____ (present in > 90% of duodenal ulcers and > 75% of gastric ulcers)
H. pylori
Peptic Ulcer Disease
Cause/ Incidence:
2. Medications such as ____, ASA, and glucocorticoids
NSAIDs
Peptic Ulcer Disease
Cause/ Incidence:
3. More common in ____ (3:1)
men
Peptic Ulcer Disease
Cause/ Incidence:
4. ____ ulcers between ages 30 to 55
Duodenal
Peptic Ulcer Disease
Cause/ Incidence:
5. ______ ulcers between ages 55 to 65
Gastric
Peptic Ulcer Disease
Cause/ Incidence:
6. More common in > ½ PPD ____
smokers
Peptic Ulcer Disease
Cause/ Incidence:
7. ____ and dietary factors do not appear to cause ulcer disease
Alcohol
Peptic Ulcer Disease
Cause/ Incidence:
8. The role of ____ is uncertain: Type A personalities?
stress
Peptic Ulcer Disease
Signs/ Symptoms
1. Gnawing _____ pain
epigastric
Peptic Ulcer Disease
Signs/ Symptoms
2. Relief of pain with eating (______)
duodenal
Peptic Ulcer Disease
Signs/ Symptoms
3. Pain worsens with eating (____)
gastric
Peptic Ulcer Disease
Physical Findings
1. Often unremarkable; may note some mild epigastric ______
tenderness
Peptic Ulcer Disease
Physical Findings
2. GI bleeding (20% of cases) Melena, hematemesis, or ____-ground emesis
coffee
Peptic Ulcer Disease
Physical Findings
3. _____ (5 to 10% of cases)” Severe epigastric pain, “board-like” abdomen, quiet bowel sounds, rigidity, and other sigmas of an acute abdomen
Perforation
Peptic Ulcer Disease
Laboratory/Diagnostics
1. Normal; may note anemia on the ____
CBC
Peptic Ulcer Disease
Laboratory/Diagnostics
2. Consider endoscopy after __ to __ weeks of treatment
8 to 12
Peptic Ulcer Disease
Laboratory/Diagnostics
3. Consider ___ -___ testing Out-Patient Management
H. pylori
Peptic Ulcer Disease
Acid-antisecretory Agents
H2 Receptor Antagonists
1. ______ (Tagamet) 800 mg/hours sleep
Cimetidine
Peptic Ulcer Disease
Acid-antisecretory Agents
H2 Receptor Antagonists
2. ______ (Zantac) 300 mg/hours sleep
Ranitidine
Peptic Ulcer Disease
Acid-antisecretory Agents
H2 Receptor Antagonists
3. _____ (Pepcid) 40 mg/hours sleep
Famotidine
Peptic Ulcer Disease
Acid-antisecretory Agents
H2 Receptor Antagonists
4. ________ (Axid) 300 mg/hours sleep
Nizatidine
Peptic Ulcer Disease
Proton Pump Inhibitors
(30 minutes before meals)
1. _____ (Prevacid) 15 mg/day
Lansoprazole
Peptic Ulcer Disease
Proton Pump Inhibitors
(30 minutes before meals)
2. ________ (Aciphex) 20 mg/day
Rabeprazole
Peptic Ulcer Disease
Proton Pump Inhibitors
(30 minutes before meals)
3. ______ (Protonix) 40 nag/day
Pantoprazole