Diabetic Drugs Flashcards

1
Q

What are thiazolidinediones? and what is the area they work on?

A

Increase lipid storage in adipose tissue reducing fat in the liver.

Peroisome proliferator - activated receptor gamma

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2
Q

Example of thiazolidinediones?

A

Pioglitazone

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3
Q

What are some Incretin agonists?

A

Exenatide

Liraglutide

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4
Q

Give five examples of sulfonylureas

A

Glibencalmide

Gliclazide

Glimepiride

Tolbutamide

Glipizide

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5
Q

Give examples of DDP-4 inhibitors blockers

A

Sidagliptin

Vidagliptin

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6
Q

Give examples of SGLT2 inhibitors

A

Canagliflozin

Dapaglifozin

Empagliflozin

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7
Q

What enzymes does metaformin inhibit?

A

Glucose - 6 - phosphatase

Phosphophenolpyruvate carboxykinase

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8
Q

What channel do sulfonylureas close?

A

K+ ATPase channels

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9
Q

Name two incretins and where they derive from:

A

Gastric Inhibitory Peptide - Duodenum

Glucagon like peptide: L cells of Ilium

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