Cytology Flashcards
What does the polarity of a cell refer to?
The number of poles (denrites and axons)
Which polarity is commonly found in neurons?
- Multipolar
Which neuron is commonly found in specialized sensory systems?
- Bipolar
Which neuron is commonly found in general senses?
- Pseudounipolar
How is a pseudounipolar neuron identified?
It is a specialized bipolar neuron in which the axon can bypass the cell body for faster propagation.
How are neurons classified according to axon length?
- Golgi I (long)
- Golgi II (short)
What do Golgi I neurons connect?
- One subsystem to another
What do Golgi II neurons connect?
- Neurons within the same subsystem
What are segmental Golgi II neurons?
- Project to the same segment (1 - 3 segments)
What are associative Golgi II neurons?
- Project ipsilaterally
What are commissural Golgi II neurons?
- Project contralaterally
What propriospinal Golgi II neurons?
- Project to other spinal column segments ( 5 - 10 - 15 segments)
What function do propriospinal Golgi II neurons perform?
- Motor reflex functions
What are tract cells?
- Golgi I neurons that only reside in the CNS
- Cells contain same information, and respond to the same modalities
- Form tracts
Which type of Golgi neuron is an interneuron?
Golgi II
What is an afferent neuron?
- Arriving to point of reference
What is an efferent neuron?
- Exiting point of reference
Which type of neuron is typically sensory?
- Afferent
Which type of neuron is typically motor?
- Efferent
What is an excitatory neuron?
- Causes an action
What is an inhibitory neuron?
- Prevents an action, or makes it more difficult
What is a modulatory neuron?
- Nervous system influences a structure or environment that makes the target neuron harder or easier to fire
What does it mean if a neuron has tonic/ regular spiking?
- The neuron is constantly firing
What does it mean if a neuron is phasic/ busting?
- Neurons fire in bursts
What does it mean if a neuron is fast spiking?
- It has fast firing rates
What are thin spike neurons?
I don’t know ???????????
What are cholinergic neurons?
Neurons that release acetylcholine
What are cholinergic neurons’ function?
- Primary stimulator to muscles
- Inhibitor of parasympathetic nervous system
What are GABAergic neurons?
- Primary inhibitors
What are glutamatergic neurons?
- Excitatory neurons
What are dopaminergic neurons?
- Excitatory neurons that release dopamine
What are serotonin releasing neurons?
- Excitatory neurons that release serotonin
What are the non-neural cells of the CNS and PNS?
- Neuroglia
By how much do glia cells outnumber neurons?
5 - 50: 1
What percentage of the total CNS is comprised of glia cells?
- 40 %
What are the 4 main functions of the glia cells?
- Development
- Support
- Nurture: (What nutrients the nuerons will and won’t receive)
- Maintenance of relatively constant environment (nutrition, and impulse conduction)
What are the most abundant neuroglia?
- Astrocytes
What type of neuron do astrocytes resemble?
- Multipolar cells
Where are fibrous astrocytes found?
In white matter
Where are protoplasmic astrocytes found?
In gray matter
What astrocytes that are found on the outside of blood vessels called?
- Perivascular glia
Where are oligodendroglia found?
Within the white matter of the CNS
What do oligodendroglia produce?
Myelin
What tissue do microglia originate from?
- Mesoderm