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MBBS CPRS > CPRS 89: Drugs used in Urinary Tract Infection > Flashcards

CPRS 89: Drugs used in Urinary Tract Infection Flashcards

1
Q

What are the components of:

Amoxicillin-Clavulanate

A

Beta-lactam

Beta-lactamase inhibitor

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2
Q

What can be used to treat cystitis

Inflammation of the bladder

A

Nitrofurantoin

Amoxicillin-Clavulanate

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3
Q

What can be used to treat Acute Pyelonephritis

What CANNOT be used to treat Acute Pyelonephritis

A

Can: Amoxicillin-Clavulanate
Cannot: Nitrofurantoin

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4
Q

What can be used to deal with

E. Coli and Klebsiella pneumoniae

A

Nitrofurantoin

Amoxicillin-Clavulanate

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5
Q

What is used to treat Enterobacter Cloacae Complex

A

Levofloxacin

Ciprofloxacin

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6
Q

What is used to treat ESBL-producing Enterobacteriaceae

A 
Fosfomycin trometamol
(Inhibiting peptidoglycan production, thus inhibit cell wall synthesis)
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7
Q

What are used to treat infection of Candida Supp. (Fungus)

A

Fluconazole

Amphotericin B

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8
Q

What are used to treat urethritis and cervicitis

A

Azithromycin

Doxycycline

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9
Q

Which 2 bacteria are responsible for causing urethritis

A

Chlamydia trachomatis

Neisseria gonorrhea

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10
Q

What microorganisms are responsible for catheter-associated UTI

A

Candida supp.

Escherichia coli

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11
Q

What is used to treat prostatitis

A

Quinolones
Ciprofloxacin
Levofloxacin

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12
Q

If the diseases are not treated, what will result

A

Pelvic Inflammatory Disease

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13
Q

When we are treating gonorrhea, what bacteria shall we always treat first?

A

Chlamydia trachomatis

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14
Q

How does Fosfomycin work

  • Irreversibly inhibits ________
  • Prevents ________ formation, which is an essential element in __________ of the cell wall
A

How does Fosfomycin work

  • Irreversibly inhibits MurA
  • Prevents NAM formation, which is an essential element in peptidoglycan of the cell wall
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15
Q

Inhibition of Folate Synthesis

  • Folate is needed for ______ synthesis in bacteria
  • PABA => Dihydrofolic acid (What drug inhibits this?)
  • Dihydrofolic acid => Tetrahydrofolic Acid (What drug inhibits this?)
A

Inhibition of Folate Synthesis
*Folate is needed for DNA synthesis in bacteria

  • PABA => Dihydrofolic acid (What drug inhibits this?)
    Sulfamethoxazole
  • Dihydrofolic acid => Tetrahydrofolic Acid (What drug inhibits this?)
    Trimethoprim
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16
Q

What is the component is Cotrimoxazole?

A

Trimethoprim : Sulmethoxazole

1 : 5

17
Q

For Nitrofurantoin

What colour of urine will it produce?

A

Brown urine

But it is harmless

MBBS CPRS (44 decks)

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